Why Is Congestive Heart Failure Treated Differently In Black Persons Compared To White Persons?

Question

I recently learned this from ck1956. Why is it and how it?

This surprises me. Or is this false?

Answer 1

No white person was person was present in that study. The study was terminated. Hence the question of comparison does not arise.
Here is a part of extract of the link given above:

Methods A total of 1050 black patients who had New York Heart Association class III or IV heart failure with dilated ventricles were randomly assigned to receive a fixed dose of isosorbide dinitrate plus hydralazine or placebo in addition to standard therapy for heart failure. The primary end point was a composite score made up of weighted values for death from any cause, a first hospitalization for heart failure, and change in the quality of life.

Results The study was terminated early owing to a significantly higher mortality rate in the placebo group than in the group given isosorbide dinitrate plus hydralazine (10.2 percent vs. 6.2 percent, P=0.02). The mean primary composite score was significantly better in the group given isosorbide dinitrate plus hydralazine than in the placebo group (–0.1±1.9 vs. –0.5±2.0, P=0.01; range of possible values, –6 to +2), as were its individual components (43 percent reduction in the rate of death from any cause [hazard ratio, 0.57; P=0.01] 33 percent relative reduction in the rate of first hospitalization for heart failure [16.4 percent vs. 22.4 percent, P=0.001], and an improvement in the quality of life [change in score, –5.6±20.6 vs. –2.7±21.2, with lower scores indicating better quality of life; P=0.02; range of possible values, 0 to 105]).
I hope you go the link and study carefully.
FALSE. people are fond of doing such vague studies, appears to more political, than any benefit to mankind.

Answer 2

1

Answer 3

Caucasians with CHF are usually treated with drugs such as lisinopril or diovan, that target the production and uptake of an enzyme called "ACE".

It's been known for some time that African Americans with hypertension don't respond well to the above drugs.

Here's a link to an article in the New England Journal of Medicine...

Answer 4

Ive heard that too. White people respond to different meds than blacks. I dont know why this is but i heard it from the TV show House.