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Pancreas and liver. The pancreas produces both insulin and glucagon, as well as other endocrines, and the liver stores glucose in the form of glycogen, which gets released when the blood sugar level falls.

2007-11-11 12:29:54 · answer #1 · answered by micksmixxx 7 · 0 0

Diabetes is indeed a multi-hormonal disease. Everybody who has responded is right. The pancreas and the liver both play key roles in maintaining glucose levels in the body. In the pancreas lie the alpha cells and the beta cells. Alpha cells secrete glucagon which, in turn, stimulates glucose output from the liver. The beta cells not only secrete insulin, but also amylin. Both insulin and amylin work together to maintain glucose homeostasis. Insulin is responsible for glucose disappearance from the blood stream, while amylin is responsible for glucose appearance into the bloodstream. Amylin does this by suppressing glucagon secretion and slowing down gastric emptying.

Wait there's more! In the L cells of the intestines, GLP-1 or incretin hormones are secreted. These hormones, unfortunately deficient in diabetics, represent the natural glucose regulating mechanism of the body, in response to food intake. GLP-1 hormones elicit many mechanisms, such as enhancing insulin secretion from the beta cells, suppressing glucagon secretion from the alpha cells, slowing down gastric emptying, enhancing first-phase insluin response, and enhancing satiety.

This is only a basic description of the many hormones involved in glucose regulation. Hope it helps.

2007-11-12 03:08:16 · answer #2 · answered by Confused_Rep 4 · 0 0

Mostly the pancreas:

Insulin is secreted by the Islets of Langerhans which are special groups of cells in the pancreas. The Islets (little islands) are endocrine organs.

If you have a large carbohydrate meal, the level of glucose in the blood will start to rise as your digestive system turns all the starch and sugars in your food into glucose.

If you have not had a meal for several hours your blood sugar level will fall because your cells use up the glucose in aerobic respiration.

When your blood sugar level rises, the Islets of Langerhans secrete MORE insulin.

When your blood sugar level falls, the Islets of Langerhans secrete LESS insulin.

The main target organ for insulin is the liver. It is the liver which removes glucose from the blood by turning it into glycogen.

All other tissues in your body need insulin to help then respire glucose, so in a way they are also target organs.

If you eat, and eat, and eat, and eat, never mind how little exercise; there will come a time when there is no more room for glycogen in your liver. High levels of insulin will make you start to turn the excess glucose into FAT. Please balance your diet!!!!!

When you fast for more than two days, your liver will run out of glycogen, so you will have to use fat and protein to get energy.

When your blood sugar level falls too low, not only does the pancreas make less insulin, but another endocrine gland, the adrenal gland, starts to make adrenalin and glucocorticoids.

Adrenalin and glucocorticoids are hormones which have the opposite effect to insulin, i.e. they help to raise blood sugar level.

The hypothalamus detects the conditions in your blood. It measures many things including blood sugar level. The hypothalamus is connected to the pituitary gland which is yet another endocrine gland.

Negative feedback is the special mechanism for turning the hormones off after they have done their job. So when your blood sugar level drops, the amount of insulin produced also falls, and when your blood sugar level has risen back to normal, the amount of adrenalin and glucocorticoids falls.

2007-11-11 12:26:09 · answer #3 · answered by confucius 3 · 1 1

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2016-05-20 10:15:56 · answer #4 · answered by ? 4 · 0 0

The pancreas and liver are involve.
In the pacreas are special cells called the Islets of Langerhans this is where the beta cells produce glucagon- raises blood glucose levels and the alpha cells produce insulin- reduces blood glucose levels. The liver stores the extra glucose as glycogen until the body needs it. Then the liver breaks the glycogen down and you have glucose again.

2007-11-11 22:29:20 · answer #5 · answered by summer4gal 1 · 0 1

Many common natural remedies are claimed to have blood sugar lowering properties that make them useful for people with or at high risk of diabetes. Learn here https://tr.im/ANr6l

A number of clinical studies have been carried out in recent years that show potential links between herbal therapies and improved blood glucose control, which has led to an increase in people with diabetes using these more 'natural' ingredients to help manage their condition.

2016-05-02 14:06:14 · answer #6 · answered by Anonymous · 0 0

In the Islet of Langerhans of our pancreas, there are two types of cells:
1. Alpha cells that produce glucagon
2. Beta cells that produce insulin.

The function of glucagon is just the opposite of the one of insulin. If insulin makes the blood glucose level lower, glucagon, on the other hand, makes the blood glucose level higher.
If the blood glucose level decreases, alpha cells are stimulated and produce glucagon. This hormone stimulates liver cells to mobilise stored glycogen into glucose.
If blood glucose level increases, the beta cells are stimulated and produce insulin.. Insulin stimulate its receptors on thecell membrane and he glucose gates are open, so more glucose molecules are sucked into the cells.

2007-11-11 14:18:09 · answer #7 · answered by Haliman S 4 · 1 0

1

2017-02-09 08:31:35 · answer #8 · answered by ? 4 · 0 0

pancreas of course

2007-11-11 12:25:10 · answer #9 · answered by Confused 3 · 0 0

pancreas

2007-11-11 12:24:34 · answer #10 · answered by L Cameezy... Simply 4 · 0 0

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