what is ramipril used for?

Answer 1

Ramipril belongs in a class of drugs called angiotensin converting enzyme (ACE) inhibitors which are used for treating high blood pressure and heart failure and for preventing kidney failure due to high blood pressure and diabetes

Answer 2

Ramipril belongs in a class of drugs called angiotensin converting enzyme (ACE) inhibitors which are used for treating high blood pressure and heart failure and for preventing kidney failure due to high blood pressure and diabetes. Other ACE inhibitors are enalapril (Vasotec), quinapril (Accupril), captopril (Capoten), fosinopril (Monopril), benazepril (Lotensin), lisinopril (Zestril, Prinivil), moexipril (Univasc) and trandolapril (Mavik). ACE is important because it produces the protein, angiotensin II. Angiotensin II contracts the muscles of most arteries in the body, including the heart, thereby narrowing the arteries and elevating the blood pressure. In the kidney, the narrowing caused by angiotensin II also increases blood pressure and decreases the flow of blood. ACE inhibitors such as ramipril lower blood pressure by reducing the production of angiotensin II, thereby relaxing the arterial muscles and enlarging the arteries. The enlargement of the arteries throughout the body reduces the blood pressure against which the heart must pump blood, and it becomes easier for the heart to pump blood. The arteries supplying the heart with blood also enlarge. This increases the flow of blood and oxygen to the heart, and this improves further the ability of the heart to pump blood. The effects of ACE inhibitors are particularly beneficial to people with congestive heart failure. In the kidneys, the enlargement of the arteries also reduces blood pressure and increases blood flow. The FDA approved ramipril in 1991.

Answer 3

Ramipril is used for reducing blood pressure. I have been taking it for about 3 years and it has stabilised my pleasure. It is not always the best drug for everybody but I find it works well for me.

Answer 4

As The Queens says ... High Blood Pressure

Answer 5

This research topic will give you inside view of this anti hypertensive medication:

General pharmacology of ramipril.

* Omosu M,
* Komine I,
* Becker RH,
* Scholkens BA.

Pharma Research Laboratories, Hoechst Japan Limited, Saitama.

General pharmacological properties of (+)-(1S,3S,5S)-2-[(S)-N-[(S)-1-ethoxycarbonyl-3-phenyl-propyl] alanyl]-2-azabicyclo[3.3.0]octane-3-carboxylic acid (ramipril, Hoe 498), a new prodrug non-sulfhydryl angiotensin converting enzyme inhibitor and its active diacid metabolite, ramiprilat, were examined. Both ramipril and ramiprilat were without effect on basal central and autonomic nervous systems in rats and mice. Ramipril given intravenously to anaesthetized normotensive dogs produced a slight fall in blood pressure but did not significantly alter other cardio-hemodynamic functions. Also, ramiprilat was without effect on isolated atria and airway resistance of guinea pigs. Oral administration of ramipril to dogs increased renal blood flow but did not significantly affect other renal parameters, for example, glomerular filtration rate and electrolyte excretion. Ramipril produced a competitive inhibition of late proximal tubular secretion which points to in part renal secretory excretion of ramipril and/or its metabolites. Compared to urea-induced diuresis in rats, ramipril was without direct diuretic activity. Ramipril exerted little, if any, influence on gastric bile and pancreatic secretion or intestinal transit in rats, as well as on concentration of glucose and lipoproteins, blood coagulation, platelet aggregation and vascular permeability in rats, rabbits or dogs. The carrageenin-induced rat paw edema was enlarged by ramipril, but there was no such effect on serotonin-, dextran- or ovalbumin-induced edemas which in contrast to carrageenin do not involve bradykinin. Thus, undesired cutaneous reactions might result from locally released bradykinin

Answer 6

High Blood pressure

Answer 7

i have ramipril and so does my husband its for high blood pressure

Answer 8

I was put on this. And they said it would help the blood flow
between the heart and the kidneys. ARVC diagnosed.

However i had to give this tablet up as the side effect of a terrible consistant cough,,, was too much!

Answer 9

usually for the treatment of coronary artery disease,it thins the blood,thus stops clots from forming

Answer 10

to treat heart disease and high blood pressure. ask a pharmacist or doctor