what is the use of solutab dexana?

Question

give the use and side effect of solutab dexana

Answer 1

TAB. DEXANA or Dexamethasone is in a class of drugs called steroids. Dexamethasone reduces swelling and decreases the body's immune response.

Dexamethasone is used to treat many different conditions. It is used to treat endocrine (hormonal) disorders when the body does not produce enough of its own steroids. It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.

SIDE EFFECTS - If you experience any of the following serious side effects, stop taking dexamethasone and seek emergency medical attention or contact your doctor immediately:

* an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
* increased blood pressure (severe headache or blurred vision); or
* sudden weight gain (more than 5 pounds in a day or two).

Other, less serious side effects may be more likely to occur. Continue to take dexamethasone and talk to your doctor if you experience

* insomnia;
* nausea, vomiting, or stomach upset;
* fatigue or dizziness;
* muscle weakness or joint pain;
* problems with diabetes control; or
* increased hunger or thirst.

Other side effects that occur only rarely, usually with high doses of dexamethasone, include

* acne,
* increased hair growth,
* thinning of the skin,
* cataracts,
* glaucoma,
* osteoporosis,
* roundness of the face, and
* changes in behavior.

For further information on Dexamethasone, please see the website at the link mentioned at source below -

Answer 2

It's dexamethasone, an oral (cortico)steroid. Despite the lengthy side effects and interactions sections below, this is a very safe and effective medication for short term use in most patients.

From http://www.medicinenet.com/dexamethasone_oral/article.htm

PRESCRIBED FOR: Dexamethasone is used to achieve prompt suppression of inflammation in many conditions. Some examples include rheumatoid arthritis, systemic lupus, acute gouty arthritis, psoriatic arthritis, ulcerative colitis, and Crohn's disease. Severe allergic conditions that fail conventional treatment may also respond to dexamethasone. Examples include bronchial asthma, allergic rhinitis, drug-induced dermatitis, and contact and atopic dermatitis. Chronic skin conditions treated with dexamethasone include dermatitis herpetiformis, pemphigus, severe psoriasis and severe seborrheic dermatitis. Chronic allergic and inflammatory conditions of the uvea, iris, conjunctiva and optic nerves of the eyes are also treated with dexamethasone.

Dexamethasone is also used in the treatment of blood cell cancers (leukemias), and lymph gland cancers (lymphomas). Blood diseases involving destruction of platelets by the body's own immune cells (idiopathic thrombocytopenia purpura), and destruction of red blood cells by immune cells (autoimmune hemolytic anemia) can also be treated with dexamethasone. Other miscellaneous conditions treated with this medication include thyroiditis and sarcoidosis. Finally, dexamethasone is used as a hormone replacement in patients whose adrenal glands are unable to produce sufficient amounts of corticosteroids."

SIDE EFFECTS: Dexamethasone side effects depend on the dose, the duration and the frequency of administration. Short courses of dexamethasone are usually well tolerated with few and mild side effects. Long term, high doses of dexamethasone will usually produce predictable, and potentially serious side effects. Whenever possible, the lowest effective doses of dexamethasone should be used for the shortest possible length of time to minimize side effects. Alternate day dosing can also help reduce side effects.

Side effects of dexamethasone and other corticosteroids range from mild annoyances to serious irreversible bodily damages. Side effects include fluid retention, weight gain, high blood pressure, potassium loss, headache, muscle weakness, puffiness of and hair growth on the face, thinning and easy bruising of skin, glaucoma, cataracts, peptic ulceration, worsening of diabetes, irregular menses, growth retardation in children, convulsions, and psychic disturbances. Psychic disturbances can include depression, euphoria, insomnia, mood swings, personality changes, and even psychotic behavior.

DRUG INTERACTIONS: Prolonged use of dexamethasone can depress the ability of body's adrenal glands to produce corticosteroids. Abruptly stopping dexamethasone in these individuals can cause symptoms of corticosteroid insufficiency, with accompanying nausea, vomiting and even shock. Therefore, withdrawal of dexamethasone is usually accomplished by gradual tapering. Gradually tapering dexamethasone not only minimizes the symptoms of corticosteroid insufficiency, it also reduces the risk of an abrupt flare of the disease under treatment.

Dexamethasone and other corticosteroids can mask signs of infection and impair the body's natural immune response to infection. Patients on corticosteroids are more susceptible to infections, and can develop more serious infections than healthy individuals. For instance, chicken pox and measles viruses can produce serious and even fatal illnesses in patients on high doses of dexamethasone. Live virus vaccines, such as small pox vaccine, should be avoided in patients taking high doses of dexamethasone, since even vaccine viruses may cause disease in these patients. Some infectious organisms, such as tuberculosis (TB) and malaria, can remain dormant in a patient for years. Dexamethasone and other corticosteroids can reactivate dormant infections in these patients and cause serious illnesses. Patients with dormant tuberculosis may require anti- TB medications while undergoing prolonged corticosteroid treatment.

By interfering with the patient's immune response, dexamethasone can impede the effectiveness of vaccinations. Dexamethasone can also interfere with the tuberculin (TB) skin test and cause false negative results in patients with dormant tuberculosis infection.

Dexamethasone impairs calcium absorption and new bone formation. Patients on prolonged treatment with dexamethasone and other corticosteroids can develop osteoporosis and an increased risk of bone fractures. Supplemental calcium and vitamin D are encouraged to slow this process of bone thinning. In rare individuals, destruction of large joints can occur while undergoing treatment with dexamethasone or other corticosteroids. These patients experience severe pain in the involved joints, and can require joint replacements. The reason behind such destruction is not clear.