I need explanation on HSV-1 blood test result... Can anyone help?

Question

I have no knowledge on HSV at all untill recently my wife genital has an outbreak. The result of my wife's diagnosis was she was infected by HSV-1. I took IgG & IgM test and IgG shows that I have HSV-1, index of 10, which indicate as positive (range shown >1.1 is positive). Negative for HSV-2. However, I do have sex with her day before her blister become visual. I took the test 2 days after that. What is the number "10" means? How the test come out with this number? Is "10" means I have a boost on antibodies which I recently transmitted from my wife? I had fever blister inside my mouth quite often due to my working environment which I think this is how I develope antibody. Me and my wife just married 2 months ago, we never had any sex partners before. We had approximately 15 or less intercourses and oral sexes after we married. Our relationship is now being test, I urgently need to know what is the meaning of the numbers which >1.1 to 10 or more means other than "positive". Thank you!

Answer 1

It's more important to know the value of the IgM. High IgM means acute and recent infection. If you have a positive IgM plus a positive IgG, then you most likely have a current, acute infection. But a high IgG number by itself (in this case 10, where any value above 1.1 is positive) indicates previous infection or exposure, and is usually a false positive because history of chicken pox can artificially cause a high IgG value.

The second answerer was right to tell you that a majority of people have HSV-1, but it's more like 60-70%, not 90% (per CDC estimates). And HSV-1 is the strain that traditionally causes oral herpes. Most people contract it nonsexually when they are babies or children. Even if you have never had a cold sore, you could still have HSV-1. However, you did say you get fever blisters, so it's likely that you DO have HSV-1 (if you were to get tested during a blister outbreak, you'd probably find that your IgM went up).

And since your wife is having genital blisters, then she may have gotten HSV-1 on her genitals, too. While this is unpleasant, it's good to know that HSV-1 doesn't do too well in that region, and she probably won't have more outbreaks. Still, both of you may benefit from some cyclovir medications to quell your outbreaks of fever blisters and such.

Lastly, even if you had sex with her right before she had her blisters, you won't get re-infected with the HSV-1. You already have it, and it's already on its prefered site.

So please don't let this interfere with your marriage. And if you've been married 2 months and only done it 15 times, then sir, you have a honeymoon to plan ;)

Answer 2

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Hsv 2 Test Results Range

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Hsv 1 Test

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RE:
I need explanation on HSV-1 blood test result... Can anyone help?
I have no knowledge on HSV at all untill recently my wife genital has an outbreak. The result of my wife's diagnosis was she was infected by HSV-1. I took IgG & IgM test and IgG shows that I have HSV-1, index of 10, which indicate as positive (range shown >1.1 is positive). Negative for...

Answer 9

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Answer 10

You should know that up to 90% of the population is infected with HSV-1. I'm surprised your doctor tested you, lots of studies show it isn't the standard of care. We usually acquire HSV-1 in childhood or perinatally, not as adults. People tend to unknowingly transmit HSV-1 (cold sores) to kids by kissing them. Genital herpes is usually due to HSV-2, but there are cases of HSV-1. You could have given your wife HSV-1 by giving her oral sex because HSV-1 is usually transmitted by saliva. But it can also be transmitted by utensils such as razors. Health care workers may also be a source of infection, although I hope that's not the case. HSV-2 is usually transmitted via sex. As far as the number "10", it doesn't really indicate anything other than a positive result. In the end, I think you're overreacting to your wife's infection. Most of us have HSV-1 and forensically speaking, there is no evidence that she had an extramarital affair. You both probably had HSV-1 since childhood. You need to forget about this and move on with your lives...

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