why do overweight people have higher chance of getting diabetes?

Question

I want to know the reason why?

Answer 1

Insulin is needed to signal liver and muscle cells to absorb glucose, and signal fat cells to absorb lipids from the blood.

The mechanisms linking obesity and diabetes are are not well understood, but it appears that fat tissue release certain chemicals into the bloodstream (fatty acids, glycerol, hormones, and others) which increases the base levels of insulin. Over time, the body's cells become accustomed to high insulin levels, and they don't respond until insulin levels are extremely high. This stage is called insulin resistance. Insulin resistance becomes diabetes when the body cannot produce enough insulin to cause the cells to absorb glucose or fat from the bloodstream.

In a person who exercises, has a low-sugar diet, and a stable weight at healthy levels, nutrients get used before they can be converted to fat or glycogen, so blood levels of insulin rise and fall and insulin resistance does not develop.

Answer 2

1

Answer 3

First of all, you must be careful not to generalize. It is only TYPE 2 diabetes that is linked with excess weight and obesity (in most but not all cases).

Type 1 diabetes, the second most common form of diabetes (5-10% of cases) is NOT related to obesity, poor diet, or lack of exercise in any way. Most people with Type 1 diabetes are thin prior to diagnosis, because it is not a lifestyle related disease. Type 1 diabetes is an autoimmune disease that requires multiple daily insulin injections for survival.

The reason why about 90% of people with Type 2 diabetes are overweight, and why overweight people are generally at risk for Type 2 diabetes has to do with *insulin resistance*.

Insulin resistance is a disorder in which the body does not respond to the insulin it makes. The cells receptors are "blind" to it. In turn, the pancreas must release large amounts of insulin into the blood to maintain glucose homeostasis (normal blood sugar). Large amounts of insulin in the blood can lead to even more weight gain. When even large amounts of insulin cannot control the blood sugar anymore, or the pancreas begins to "wear out", this is called Type 2 diabetes. It is a never ending cycle if nothing is done.

So you can see that insulin resistance is both a result of and a casue of obesity and eventually Type 2 diabetes.

Ways to prevent insulin resistance in the first place are: losing weight, eating healthy and exercising, switching any medications that may raise the risk for insulin resistance like steroids, and taking a drug known to help like Metformin if you are at high risk for Type 2 diabetes (this has been tried in some studies).

The *exact* mechanisms for insulin resistance are not clear, but it appears to be that hormones released from fat cells (yes fat cells are an endocrine organ!) block the cell's receptors to insulin, as does chronic inflammation. Both can be helped or reduced by weight loss, regular exercise, and a healthy diet with no processed foods.

There are cases of genetic insulin resistance which are not lifestyle related (generally people who have Type 2 diabetes and are thin), but the vast majority of cases do have a link with lifestyle habits. These genetic cases may be cause by genetically defective insulin receptors.

Since Type 2 diabetes is becoming an epidemic along with obesity, there is much research going on in this area. Some evidence points to viruses and toxins playing a role in causing insulin resistance. While this may be true, trans fats (found in junk and processed foods) have been CLEARY linked to Type 2 diabetes. In the vast majority of cases, a clean healthy diet and exercise should prevent or delay a lot of the cases we're seeing now.

Answer 4

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Answer 5

weight has nothing to do with whether u have diabetes or not. Recent research suggest that only 5% of obese people are diabetic. Its genetic, u gonna get it whether ur obese or not. I wish i can find that research report and i will post it here . I just found the site here is the link and remove the myth that obeseity has any relationship with diabetes.

http://www.nytimes.com/2007/08/20/health/20diabetes.html?_r=1&hp=&adxnnl=1&oref=slogin&adxnnlx=1187593209-u2zrdALFdz+iVsIyWDfvpQ

Good Luck

Answer 6

Yes, obesity is linked to diabetes. It isn't exactly clear on how. But overnuitrition dampens the insulin receptors. A series of reactions leads to insulin resistance prior to diabetes, this occurs during the pre-diabetic stage when glucose level is high but not high enough to be diabetes.

Answer 7

When you eat sugars (they're in all processed foods), your body produces insulin to handle the sugar (that's usually the time when your sugar level drops dramatically). What is also happening is that the sugar interferes with your body converting it and using it, instead it stores it in your body as fat. The more fat you have, the more likelihood that what you're eating is not being digested or removed from the body (sugars in the form of starch: rice, pasta, potatoe, bread) but is in storage. After constant barraging the body with so much sugars, your insulin receptors is no longer sensitive, and your sugar levels climb to a point where you can faint. You are in the beginning stages of Diabetes where you require help to lower your sugar level.

I hope this helps.

Answer 8

their body weight is too much for the pancreas to produce enogh insulin for their size

Answer 9

absolutly!!!!!!!!!! the more over weight you are the chances of having it goes through the roof.