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hiya, The reason why grapefruit juice is a problem for people taking certain drugs - including many psychotropic meds - is that grapefruit juice (unlike any other citrus juice) inhibits two enzymes that are important in metabolizing, or breaking down, these medications. When the enzymes aren't doing their job, much more of the drug in question remains available to enter the patient's bloodstream, and in some cases, this can have dangerous, even toxic, effects.
For example, as much as 99% of BuSpar (Buspirone) is normally metabolized before the drug ever enters the bloodstream. When taken in the presence of grapefruit juice (not even at the same time), the amount of BuSpar in the system could increase as much as 400% - a hazardous situation.

According to Graedon's Guide to Grapefruit Interactions, "The grapefruit interaction is long-lasting.

... investigators have found that the effect is measurable for at least 24 hours and may linger up to two days." This could mean that if a person drank grapefruit juice every day, there would be an extra-strength "grapefruit effect" in his system all the time, as the effect of yesterday's glass might still be lingering when today's glass was drunk.
Besides the ones listed above, psychotropic medications that can be affected to a greater or lesser degree by grapefruit juice include:

Anafranil - i was on this
Clozaril
Elavil
Halcion
Haldol
Luvoxx
Seroquel
Serzone
Trazodone
Valium
Versed
Zoloft
There are a large number of other types of medications affected by grapefruit juice as well, including all the cholesterol-lowering statins and even some antibiotics and birth control pills. Always read all the literature that accompanies your new prescriptions. Just for example, on my prescription for Zocor, buried three-quarters of the way down in the fifth paragraph, "Cautions," is "Talk with your doctor before including grapefruit or grapefruit juice in your diet while you are taking this medicine." That doesn't seem to me to be a strong enough warning - but at least it's there.

2007-10-15 05:01:49 · answer #1 · answered by Missy Me xx 3 · 2 0

You shouldn't eat grapefruit (or drink grapefruit juice) if you take statins.

Take a look at the following pages for an explanation why.

2007-10-15 08:12:27 · answer #2 · answered by micksmixxx 7 · 2 0

Its True just looked at the leaflet says nothing,but pharmacist
has put on lable Avoid comsumption of grapefruit juice.

2007-10-15 05:00:47 · answer #3 · answered by Carol B 5 · 1 0

It is true, my mother is diabetic and misses eating grapefruit. Can't remember why, but definitely true.

2007-10-15 04:59:26 · answer #4 · answered by pirate_princess 7 · 0 0

Diabetes is usually treated through a combination of diet (low sugar), exercise and medications/insulin. Milder cases can be controlled with just diet an/or exercise while more severe cases require meds or insulin as well.
Learn more https://tr.im/evWUv

2015-01-30 21:10:41 · answer #5 · answered by Anonymous · 0 0

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