Propranolol & Klonopin?

Question

Does anyone know if there are any interactions between Klonopin (tranquilizer) and Propranolol (Beta Blocker)?

Both are prescribed for severe social anxiety disorder.

Inderal - 10mg
Klonopin .5mg

Thanks everyone. :)

Answer 1

Generally, there shouldn't be unless you get some increased fatigue. Propranolol can cause this as can Klonopin. The best way to avoid it is to take them at different times during the day.

if you have to take the Klonopin at bedtime, consider the propranolol during the day..unless you need to get to sleep then this could be a benefit!

I have many patients on both drugs and usually there are no problems. If you think there is a reaction or problem, call your doctor or check with your pharmacist.

MBetz, MS RPA-C
Physician Assistant

http://www.headache-adviser.con

Answer 2

The Klonopin and Seroquel both have sedative effects. Were they prescribed by the same doctor? If not, you should make sure your docs know what meds you're on before they prescribe. Layering the drugs on top of each other seems like it could be dangerous - too much sedation, and you could stop breathing.

Answer 3

The interaction you are thinking of is probably propranolol and clonidine. Klonopin and clonidine sound alike and are occasionally confused. There is a significant interaction between propranolol and clonidine, not between propranolol and Klonopin.

Answer 4

You may feel drowsy.

Klonopin is something I took for years. I kind of wish I hadn't. I didn't start dealing with issues until I stopped taking klonopin. Do me a favor and don't take it for 15 years before you decide to deal with your anxiety.

Answer 5

The information I found on [e-mail] suggests an interation between the two. Check with your doctor asap. Just because they're doctors doesn't mean they can't accidentally overlook something. A doctor with the right attitude won't hestitate to make sure that the two can be taken together.

Answer 6

yes, there are indeed interactions. Both cause a decrease in blood pressure albeit thru different routes. Still one can potentiate the other thereby causing a sudden and unpleasant and potentially dangerous drop in blood presssure. Would consult your prescriber.

Answer 7

Clonazepam side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, irritable, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have a serious side effect such as:
- confusion, hallucinations, unusual thoughts or behavior;
- weak or shallow breathing;
- unusual risk-taking behavior, no fear of danger;
- unusual or involuntary eye movements;
- pounding heartbeats or fluttering in your chest;
- painful or difficult urination, urinating less than usual;
- pale skin, easy bruising or bleeding; or
- new or worsening seizures.
Less serious side effects may include:
- drowsiness, dizziness, problems with thinking or memory;
- tired feeling, muscle weakness, loss of balance or coordination;
- slurred speech, drooling or dry mouth, sore gums;
- runny or stuffy nose;
- loss of appetite, nausea, diarrhea, constipation;
- blurred vision;
- headache;
- sleep problems (insomnia);
- skin rash; or
- weight changes.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)


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