a newborn is diagnosed with sickle cell anemia a genetic disease in which substitution of one amino acid results in abnormal hemoglobin. explain to the parents how the substitution can have such a drastic effect on the structure of the protein.
2007-10-11 06:34:36 · 2 answers · asked by lindi 2 in Science & Mathematics ➔ Medicine
In sickle cell hemoglobin (HbS) glutamic acid in position 6 (in beta chain) is mutated to valine.
Parents don`t ask for nor understand about pathological hemoglobins.
2007-10-11 22:09:24 · answer #1 · answered by J.SWAMY I ఇ జ స్వామి 7 · 0⤊ 0⤋
I'm not going to do your homework for you, but you might want to consider how primary, secondary, tertiary and quarternary protein structures may affect that protein's function.
http://matcmadison.edu/biotech/resources/proteins/labManual/chapter_2.htm
http://matcmadison.edu/biotech/resources/proteins/labManual/images/220_04_114.png
2007-10-11 12:17:19 · answer #2 · answered by Pangolin 7 · 0⤊ 1⤋