This topic is discussed in detail:
It's an ACE inhibitor.
Diseases:
1)Hypertension
Captopril (captopril tablets, USP) is indicated for the treatment of hypertension.
It can be given sublingual to lower BP/Angina.
2)Captopril may be used as initial therapy for patients with normal renal function, in whom the risk is relatively low. In patients with impaired renal function, particularly those with collagen vascular disease, captopril should be reserved for hypertensives who have either developed unacceptable side effects on other drugs, or have failed to respond satisfactorily to drug combinations.
Captopril is effective alone and in combination with other anti-hypertensive agents, especially thiazide-type diuretics. The blood pressure lowering effects of captopril and thiazides are approximately additive.
3)Heart Failure/CCF.
Captopril is indicated in the treatment of congestive heart failure usually in combination with diuretics and digitalis. The beneficial effect of captopril in heart failure does not require the presence of digitalis, however, most controlled clinical trial experience with captopril has been in patients receiving digitalis, as well as diuretic treatment.
4)Left Ventricular Dysfunction After Myocardial Infarction
Captopril is indicated to improve survival following myocardial infarction in clinically stable patients with left ventricular dysfunction manifested as an ejection fraction ≤40% and to reduce the incidence of overt heart failure and subsequent hospitalizations for congestive heart failure in these patients.
In considering use of captopril tablets, USP it should be noted that in controlled trials ACE inhibitors have an effect on blood pressure that is less in black patients than in non-blacks. In addition, ACE inhibitors cause a higher rate of angioedema in black than in non-black patients.
2007-07-13 07:36:38
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answer #1
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answered by Dr.Qutub 7
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Captopril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and some types of congestive heart failure. Captopril was the first ACE inhibitor developed and was considered a breakthrough both because of its novel mechanism of action and also because of the revolutionary development process. Captopril is commonly marketed by Bristol-Myers Squibb under the trade name Capoten.
2007-07-12 22:08:36
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answer #2
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answered by Anonymous
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Captopril is a Angiotensin-Converting Enzyme (ACE) Inhibitor. It is used for management of hypertension; treatment of CHF; in post-MI patients, and improves survival in clinically stable patients with left-ventricular dysfunction.
2007-07-13 02:58:05
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answer #3
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answered by Harmony 6
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Nothing fancy, right to the point: It's used to treat high blood pressure, and used in conjunction with other meds to treat Congestive Heart Failure.
2007-07-12 22:59:37
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answer #4
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answered by M. Rod 4
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