who invented (FENTANYL) what was his name??????

Question

Is it one big cover-up

Answer 1

Fentanyl is an opioid analgesic, first synthesized by Janssen Pharmaceutica (Belgium) in the late 1950s, with an analgesic potency of about 80 times that of morphine. Fentanyl was introduced into medical practice in the 1960s as an intravenous anesthetic under the trade name of Sublimaze. Fentanyl has an LD50 of 3.1 milligrams per kilogram in rats, and, 0.03 milligrams per kilogram in monkeys. The LD50 in humans is not known. In the United States, fentanyl is a Schedule II drug.

Fentanyls are extensively used for anesthesia and analgesia, most often in the operating room and intensive care unit. Duragesic, by Janssen Pharmaceutica, is a fentanyl transdermal patch used in chronic pain management. Duragesic patches work by releasing fentanyl into body fats, which then slowly release the drug into the blood stream over 72 hours, allowing for long lasting relief from pain. In the past few years, the patches have gone generic and are available for lower costs. Duragesic is manufactured in five patch sizes: 12.5 micrograms/h, 25 µg/h, 50 µg/h, 75 µg/h, and 100 µg/h. Dosage is based on the size of the patch, since the transdermal absorption rate is generally constant at a constant skin temperature. Rate of absorption is dependent on a number of factors. Body temperature, skin type and placement of the patch can have major effects. The different delivery systems used by different makers will also affect individual rates of absorption.

Answer 2

Cover up? What are you on? (Probably not fentanyl)

Fentanyl has been around since Paull Janssen (founder of Janssen Pharmaceutical) sythesized it in 1960. We use it all the time in anesthesia. It works fast and is less likely to make you vomit than many other opiates.

And it costs pennies. It's a great drug. It's a rare patient who meets me and doesn't get some fentanyl.

Answer 3

Fentanyl was first synthesized by Janssen Pharmaceutica (Belgium) established by Dr. Paul Janssen in the late 1950s.

Answer 4

Patent in US (3,141,823) granted 1964 to Janssen. Gardocki also mentioned in the development. An amazing narcotic. 1000 times more potent than morphine?