microbiogoy question i bet noone can answer?

Question

Within 3 day period at a large hospital, 5 patients under going hemodialysis developed fever and chills. Pseudomonas, aeruginosa, and klebsiella were isolated from the three of the patients. P aeruginosa K pneumonia and enterobacter were isolated from the dialysis system. Why do all three bacteria cause similar symptoms?

Answer 1

Each of these organisms are gram negative, fever and chills are probably the most common of symptoms for a gram negative microorganism to cause.
The body initiates a fever when it senses a foreign organism in order to create a less hospitable environment. However when gram negative organisms die they release endotoxin A which is extremely toxic to the human body this sends the body into shock, blood pressure lowers, and chills occur. In the hospital environment, most deaths occur from the shock because there's no way to counteract the endotoxin in time and the patient tends to already be weak from previous illness

Answer 2

Your body mounts a very complex defense to any invading organism; called the sepsis (or SIRS--systemic inflammatory response) cascade. In effect, cellular and molecular substances (called Tumor Necrosis Factor and Interleukins, among others ) are released in response to bacterial proteins. These act to cause, among a number of other signs, an elevated temperature (fever), while bacterial bursts in the blood cause the rigors or chills. All three bacteria are classified as Gram negative; and the gram negative protein coats on these bacteria ellicit the same response. They also cause your white cells to rise & then fall in number as well as migrate to the site of the invasion, in pneumonia they cause the leaky capillary syndrome that results in pulmonary edema. This uniform response is why it is difficult to know what a septic patient is infected with until cultures grow out.

Answer 3

the body reacts in a similar fashion to all pathogens.