Idiopathic dilated cardiomyopathy (IDC) is a myocardial disease characterised by ventricular dilatation, impaired contractility, and the symptoms of congestive heart failure. Although the causes of IDC remain uncertain, much interest has been focused on the enteroviral infection in the myocardium in the pathogenesis of this disease. Enteroviral RNA has been demonstrated in the myocardium at all stages of IDC. Recent studies using sequence analysis of enteroviral polymerase chain reaction (PCR) products have shown that the viruses detected in hearts of patients with IDC are coxsackie B. In addition, active coxsackieviral RNA replication in the myocardium has been demonstrated by strand-specific detection of viral RNA. Viral antigen has also been found in hearts with IDC by immunohistochemical techniques. In tissue culture experiments and transgenic mice, it has been shown that restricted coxsackieviral RNA replication, and not infectious virus progeny, in the myocardium can impair cardiac contractile function and lead to dilated cardiomyopathy. Coxsackieviral RNA in the myocardium can be a marker of a poor clinical outcome after partial left ventriculectomy, and might influence prognosis after heart transplantation. Therefore, there is a therapeutic need to detect replicating coxsackieviral RNA in the myocardium, and a specific therapy for coxsackie B viruses is indicated in the management of patients with virus-positive IDC.
MORE THAN 1000 VIRUSES ARE KNOWN TO CAUSE VIRAL CARDIOMYOPATHY, BUT FOR SECURITY REASONS THEY ARE NOT DISCLOSED.
2007-05-30 08:02:06
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answer #1
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answered by Dr.Qutub 7
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i don not know which virus cause cardiomyopathy, but my husband had cardiomyopathy and the doctors said it was down to a virus he picked up. (he had a cold and a cough for weeks and he never got well from there, until he recieved a transplant a few years ago) He had a biopsy of his old heart and that is what came back.
Scary that anyone can get a cold.
2007-06-01 08:16:25
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answer #2
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answered by 2plus3 3
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Multiple different viruses have caused viral cardiomyopathy. It does not change the management of a patient with this, and so we do not usually search for the exact virus that caused it. But there are tests if the patient absolutely needs to know. some of the more common viruses-- coxsackie B virus, Parvo B19, enteroviruses, adenoviruses, cytomegalovirus, and less frequently Epstein-Barr virus, and influenza virus.
2007-05-30 04:43:05
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answer #3
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answered by MedIntern 2
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As previously stated, there are lots of viruses that could be the cause. My cardiomyopathy was caused by the chicken pox virus that gave me a severe case of shingles a few years ago.
2007-05-30 04:58:01
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answer #4
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answered by Andee 6
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There are a number of viruses that can cause cardiomyopathy, so the only person that can accurately answer your question is your healthcare provider.
Sorry I couldnt answer more of your question but I did find a website that might help you understand a little bit more about cardiomyopathy.
Hope this helps!!!!
2007-05-30 04:42:22
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answer #5
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answered by Anonymous
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To get to your heart, it has to be in the blood.
Likely a cut or possibly gum disease. I had a virus cause mitral valve leaflet swelling. Good oral hygiene. Take care of skin injuries., even little ones.
2007-05-30 07:39:02
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answer #6
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answered by Laurence W 6
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I think you need to ask you doctor or cardiologist about this as they maybe be able to pin point it. I have heart problems and their is no one better than a cardiologist
2007-05-30 04:34:45
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answer #7
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answered by Pinkflower 5
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ARE YOU AT ALL A GEMINI STAR SIGN?
2007-05-30 04:30:45
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answer #8
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answered by LETTER BOX 3
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