How do you manage malignant hypertension?

Answer 1

Malignant hypertension is usually defined as very high blood pressure with swelling of the optic nerve behind the eye, called papilledema (grade IV Keith-Wagner hypertensive retinopathy). Malignant hypertension is usually accompanied by other organ damage like heart failure, kidney failure, and hypertensive encephalopathy.

Hospitalization is essential until the severe high blood pressure is under control. Medications delivered through an IV line, such as nitroprusside, nitroglycerin, or others, may reduce your blood pressure.

After the severe high blood pressure is brought under control, anti-hypertensive medications taken by mouth can control your blood pressure. The medication may need to be adjusted occasionally..

Answer 2

Malignant hypertension is usually defined as very high blood pressure with swelling of the optic nerve behind the eye, called papilledema (grade IV Keith-Wagner hypertensive retinopathy). Malignant hypertension is usually accompanied by other organ damage like heart failure, kidney failure, and hypertensive encephalopathy.

This article given below is helpful :
BACKGROUND: Activation of the renin-angiotensin system has been implicated strongly in the transition from benign to malignant hypertension. However, the concomitant rise in blood pressure might also have a direct effect on the vascular wall by initiating fibrinoid necrosis and myointimal proliferation. Ascertaining the relative importance of these two factors in this process has proved difficult. TGR(mREN2)27 heterozygotes (HanRen2/Edin- -) have previously been shown to develop malignant hypertension spontaneously and exhibit the characteristic features of human malignant hypertension. OBJECTIVE: Tissue renin-angtiotensin systems have been implicated in the pathogenesis of malignant hypertension. We set out to determine whether inhibition of this system might protect against development of the disease in a rat model. METHOD: Male TGR(mREN2)27 heterozygotes (n = 24) were given a non-hypotensive dose of the angiotensin converting enzyme inhibitor ramipril (5 microg/kg per day) from 28 to 120 days of age, untreated rats acting as controls (n = 40). The incidences of malignant hypertension were compared. Systolic blood pressure was measured by tail-cuff plethysmography during treatment; tissue and plasma angiotensin converting enzyme levels and renal histological changes were assessed at the end of the treatment period or upon development of malignant hypertension. RESULTS: Sixty-three per cent of control rats and 4% of angiotensin converting enzyme inhibitor-treated rats had developed malignant hypertension by 120 days despite there having been no significant difference in systolic blood pressure throughout the course of treatment. Angiotensin converting enzyme activities in kidney, heart and resistance vessels, though not that in plasma, were significantly lower in the treated rats. The degree of medial wall thickening did not differ between the two groups whereas evidence of tissue injury (e.g. intimal fibrosis, fibrinoid necrosis and nephron injury) was significantly less common among rats in the angiotensin converting enzyme inhibitor-treated group. CONCLUSIONS: Tissue angiotensin converting enzyme inhibition at a non-hypotensive dose almost completely prevented mortality from malignant hypertension and significantly reduced tissue injury in this model, implicating angiotensin II rather than high blood pressure as the principal 'vasculotoxic' agent in malignant hypertension.
IT CAN ALSO BE CLASSIFIED AS AN MEDICAL EMERGENCY DUE TO END ORGAN DAMAGE WHICH CAN BE PERMANANT.

Answer 3

You treat the hypertension first with medication. Ususally drips to get the meds in fast to lower the pressure. Then, see what you can salvage out of the organ damage. Treat the organ damage accordingly. Brain, heart, and kidneys. Life span of this condition is usually 1- 3 years. Just what I've seen in my experience.

Answer 4

this is a medical emergency that can result in a bleed in multile body organs includng a hemmorhagic stroke or aneurysm rupture.

Immedate hospital admisson and intravenous infusion control of the blood pressure (Beta blockers...etc). patient requires further investgation to rule out causes like pheochromocytoma, thyroid storm or eclamsia if pregnant.

Malignant hyperthemia can cause high B.P but is a different medical problem.

Answer 5

Dear, malignant hypertension is an emergency, first of all u should admitt the patient to a fully equiped hospital, than to reduce the B.P., u go for sod. nitroprusside or sublingual nefdipine, than investigate for cause. According to underlying cause treat the patient.

Answer 6

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Answer 7

their are no specific treatments,doctors judge how high the hypertension is and treat it accordingly

Answer 8

Medicine is crucial, diet, proper exercise, little to no salt. Get your doctor's recommendations before you try anything on your own.