Could anyone tell me more about the effect of atropine and histamine together on smooth muscle? Would both of the drugs exert contractile force on smooth muscle or have relaxing effect? If possible, could you include the reference? Thanks
2007-03-25 17:00:05 · 2 answers · asked by student_lee 1 in Science & Mathematics ➔ Medicine
Histamine prevents bronchiolar or gastrointestinal smooth muscle constriction. Atropine also relaxes smooth muscle tissue.
http://www.pharmacology2000.com/Autonomics/Cholinergics/Cholin2.htm
2007-03-25 17:34:41 · answer #1 · answered by Anonymous · 0⤊ 0⤋
Atropine is an alkaloid of Atropa belladona .Atropine is a parasympatholytic drug . Histamine is an amine of amino acid Histidine.
Target cells of histamine are basophils and mast cells.
So it is dangerous to mix these two and the mixture will be life threatening.
2007-03-26 09:52:47 · answer #2 · answered by J.SWAMY I ఇ జ స్వామి 7 · 0⤊ 0⤋