heart attack??

Question

can anyone help me to explain on how heart attack can b detected by blood test? what are the enzymes that present in blood which indicate that person is suffering heart attack?

Answer 1

Well, to start with, it's important to understand that not all proteins in the body are produced by all cells, some cells produce more of one product than others, and some proteins (and other molecules) are found in significant concentrations only in certain cells.
This is important because the laboratory tests to help us diagnose an MI (myocardial infarction, the death of heart tissue, heart attack) make use of this fact. They are tests for creatinine phosphokinase (CPK) and troponin I or T, both of which are found in high concentrations in heart tissue and very low concentrations in blood and other cells (CPK is found in all muscles, but troponin is more specific for heart cells).
When part of the heart becomes starved of oxygen and dies, the proteins outside of it spill out, and can be detected in the blood, and that's what we look for, in a healthy person they are present in low levels, but when these levels rise, it's suspicious for a heart attack.

Answer 2

There are actually several different enzymes that can be tested. These are: myoglobin, CK-MB, troponin-T and troponin-I. All of these are normal proteins found in heart muscle cells, and when the heart is damaged from a heart attack, the cells basically disintegrate and release these proteins into the bloodstream where they can be detected with a blood test.

The most commonly used ones are myoglobin and troponin (I or T, depending on the institution). Myoglobin has the benefit of being the earliest detectable protein after a heart attack, becoming elevated at 2-4 hours after the event and peaking at 5-9 hours after the event. The downside is that this protein is found in all muscles cells, not just heart muscle, and can therefore lead to a false positive.

Because of this, the other test that we do is a troponin. This has the advantage of being specific to heart muscle. In other words, if the troponin is elevated, there is very little other than heart damage that could be the cause. The downside is that it takes 4-6 hours after a heart attack to become elevated, so if someone comes in to the ER three hours after the start of a heart attack and you ONLY rely on the troponin, you may falsely reassure yourself that the patient is not having a heart attack and postpone appropriate treatment.

Answer 3

1

Answer 4

Certain enzymes show up in the blood indicating heart muscle damage after a heart attack.

Answer 5

They test troponin levels that are specific to cardiac muscle. These are released after cells die due to ischemia.

Answer 6

it's a serious case and if you feel something you should contact your doctor immediately