2007-03-10 00:02:45 · 7 answers · asked by Anonymous in Health ➔ Diseases & Conditions ➔ Diabetes
nsulin
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Note: This article title may be easily confused with inulin.
Insulin
Insulin crystals
Other names: insulin
Genetic data
Locus: Chr. 11 p15.5
Gene code: HUGO/INS
Gene type: Protein coding
Protein Structure/Function
Molecular Weight: 5808 (Da)
Structure: Solution Structure of Human pro-Insulin Polypeptide
Protein type: insulin family
Functions: glucose regulation
Domains: INS domain
Motifs: SP motif
Other
Taxa expressing: Homo sapiens; homologs: in metazoan taxa from invertebrates to mammals
Cell types: pancreas: beta cells of the Islets of Langerhans
Subcellular localization: extracellular fluids
Covalent modifications: glycation, proteolytic cleavage
Pathway(s): Insulin signaling pathway (KEGG); Type II diabetes mellitus (KEGG); Type I diabetes mellitus (KEGG); Maturity onset diabetes of the young (KEGG); Regulation of actin cytoskeleton (KEGG)
Receptor/Ligand data
Antagonists: glucagon, steroids, most stress hormomes
Medical/Biotechnological data
Diseases: familial hyperproinsulinemia, Diabetes mellitus
Pharmaceuticals: insulin (Humulin Novolin), insulin lispro (Humalog), insulin aspart (Novolog), insulin detemir (Levemir), insulin glargine (Lantus), etc
Database Links
Codes: EntrezGene 3630; Mendelian Inheritance in Man (OMIM) 176730; UniProt P01308; RefSeq NM_000207
Insulin (from Latin insula, "island", as it is produced in the Islets of Langerhans in the pancreas) is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, it has effects on fat metabolism and it changes the liver's activity in storing or releasing glucose and in processing blood lipids, and in other tissues such as fat and muscle. The amount of insulin in circulation has extremely widespread effects throughout the body.
Insulin is used medically to treat some forms of diabetes mellitus. Patients with type 1 diabetes mellitus depend on external insulin (most commonly injected subcutaneously) for their survival because of an absolute deficiency of the hormone. Patients with type 2 diabetes mellitus have insulin resistance, relatively low insulin production, or both; some type 2 diabetics eventually require insulin when other medications become insufficient in controlling blood glucose levels.
Insulin is composed of 51 amino acid residues and has a molecular weight of 5808 Da.
Insulin's structure varies slightly between species of animal. Insulin from animal sources differs somewhat in regulatory function strength (ie, in carbohydrate metabolism) in humans because of those variations. Porcine (pig) insulin is especially close to the human version.
2007-03-10 00:47:08 · answer #1 · answered by Anonymous · 3⤊ 0⤋
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2016-05-20 00:25:20 · answer #2 · answered by Simon 3 · 0⤊ 0⤋
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2016-09-18 09:34:34 · answer #3 · answered by Jeniffer 3 · 0⤊ 0⤋
Insulin is a polypeptide hormone that regulates carbohydrate metabolism. It has effects on fat metabolism and it changes the liver's activity in storing or releasing glucose and in processing blood lipids, and in other tissues such as fat and muscle. The amount of insulin in circulation has extremely widespread effects throughout the body.
Insulin is required for all animal (including human) life.
2007-03-10 06:49:12 · answer #4 · answered by heathermagoo13 3 · 1⤊ 0⤋
I'm so sorry to hear that. It was a very well written poem. I liked the line "A creature went through it's entire life and it never felt any different." the most. Best wishes.
2016-03-28 22:34:36 · answer #5 · answered by Anonymous · 0⤊ 0⤋
To be more specific, it "unlocks" the cell walls to allow the glucose to enter. Without that, we could not survive. Pretty important.
2007-03-10 00:47:12 · answer #6 · answered by Mr. Peachy® 7 · 1⤊ 2⤋
it regulates blood sugar, something the pancreas should do without it you could die
2007-03-10 00:07:16 · answer #7 · answered by Billie R 4 · 1⤊ 0⤋