Overview of Duchenne's Disease:
Degeneration of the posterior roots and column of the spinal cord and the brain stem. Characterized by attacks of pain, progressive ataxia, loss of reflexes, functional disorders of the bladder, larynx, and gastrointestinal system, and impotence. The disease is a broad one that is divided into:
1. spinal muscular atrophy.
2. progressive bulbar paralysis.
3. tabes dorsalis.
4. Duchenne's muscular dystrophy.
Overview of Huntington's Disease:
Huntington's disease (HD) is a hereditary progressive neurodegenerative disorder characterized by the development of emotional, behavioral, and psychiatric abnormalities; loss of previously acquired intellectual or cognitive functioning; and movement abnormalities (motor disturbances). Also known as Huntington's chorea, the disorder is named for the American physician who initially described the condition in 1872.
The classic signs of HD include the development of chorea–or involuntary, rapid, irregular, jerky movements that may affect the face, arms, legs, or trunk–as well as the gradual loss of thought processing and acquired intellectual abilities (dementia). There may be impairment of memory, abstract thinking, and judgment; improper perceptions of time, place, or identity (disorientation); increased agitation; and personality changes (personality disintegration). Although symptoms typically become evident during the fourth or fifth decades of life, the age at onset is variable and ranges from early childhood to late adulthood (e.g., 70s or 80s).
HD is transmitted within families as an autosomal dominant trait. The disorder occurs as the result of abnormally long sequences or "repeats" of coded instructions within a gene on chromosome 4. The progressive loss of nervous system function associated with HD results from loss of neurons in certain areas of the brain, including the basal ganglia and cerebral cortex.
2007-03-09 14:19:01
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answer #1
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answered by HoneyBunny 7
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Duchenne's disease: A disease consisting of three neurological conditions: spinal muscular atrophy, bulbar paralysis and tabes dorsalis.
Introduction
Huntington's disease (Huntington's chorea) is a progressive, degenerative disease that causes certain nerve cells in your brain to waste away. As a result, you may experience uncontrolled movements, emotional disturbances and mental deterioration. The disorder was documented in 1872 by American physician George Huntington. The name "chorea" comes from the Greek word for "dance" and refers to the incessant quick, jerky, involuntary movements that are characteristic of this condition.
Huntington's disease is an inherited disease. Signs and symptoms usually develop in middle age, and men and women are equally likely to develop the condition. Younger people with Huntington's disease often have a more severe case, and their symptoms may progress more quickly. Rarely, children may develop this condition.
2007-03-09 14:12:31
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answer #2
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answered by omygosh 4
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