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2007-01-26 23:22:08 · 2 answers · asked by Suzyq S 1 in Health Diseases & Conditions Respiratory Diseases

2 answers

The main active compound in Lobelia inflata is a chemical called lobeline. From what I gather, it is either a blocker of the nicotine receptor, a stimulator of the nicotine receptor, or a blocker of dopamine. One study found that rats did not respond as much to amphetamine when given lobeline first: this implies that lobeline blocks the release or binding of dopamine. Xanax, on the other hand, works by enhancing the action of the receptor for GABA: it is a generalized depressant of the central nervous system. The biggest acute concerns when using Xanax are: 1) it can suppress the breathing drive at high doses, or 2) it can cause so much sedation that the patient is not able to protect his airway. Any drug that also does one or both of these is therefore dangerous when taken with Xanax. From what I have read, lobeline is not particularly sedating, and it increases breathing in animal studies (in horses, at least). On the other hand, one of lobeline's main uses is actually to cause vomiting. This could be a problem if the patient is sedated from the Xanax, because the person could breath in (aspirate) the vomit. As such, I wouldn't recommend mixing them, but I tend to err on the side of caution. You should probably discuss this with your doctor.

2007-01-26 23:54:30 · answer #1 · answered by Nicole B 5 · 0 0

There is a medication call Chantix which does the same thing as the lobelia inflata but it just costs more. I did a cheak of there interaction on http://www.drugdigest.org/DD/Home and they stated that the only that will hurt you is to talk with alcohol

2007-01-26 23:36:28 · answer #2 · answered by fxysxysrkly 4 · 0 0

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