What is latest successful treatment of epilepsy. Please guide me for that.?

Question

I have 2 epileptic patients whose fits are controlled but I want it should be cured permanently. Would someone guide me to the latest medicines or other medical procedures in this regard. Thanks

Answer 1

About 10 yrs back I had several fits which even went to the major level. The doctors had prescribed dilantin and said I would necessarily have to take this tablet the rest of my life. I never took the tablets as prescribed, but instead found the the greatest relief when I came out of the fit. Each and every muscle of the body stretched to the fullest extent parallels a fit to ***. This may be bad advice but it worked for me. Purely the power of the mind, which was also earlier the cause of the fits.

Answer 2

First of all...it is seizures not "fits"...and there is no cure for epilepsy...there are 57 known forms of epilepsy and control of the seizures is the best that can be accomplished. Seizures can be mild, even involuntary ticks can be considered a seizure, up to the Gran Mall Seizure, which is the most violent form. Epilepsy stems from brain damage... it is not a disease, head injuries are the most common cause...called acquired epilepsy.
Next your patients would best benefit from someone who gets informed and stops calling it fits! Frankly you don't sound qualified in any way to treat them or care for them. If they are already on medication and under a doctors care..they are already receiving correct and up to date care...don't change anything, or stop giving these people their medications. I have no idea if you are actually trying to help or have some other agenda, but do not take them off medications or attempt some crazy cure.

Answer 3

do not play any variety of video games. while you're having seizures there are 2 drugs on the marketplace used to handle and help avert seizures. One is dilantin and the different one is Phenytek. Ask your well being care provider what's sturdy for you simply by fact it relies upon on the severity of your epilepsy.

Answer 4

It's funny that you ask this because i'm currently in a clinical trial for an experimental drug for epilepsy. Its called Lacosamide. The pharmaceutical website i looked at said that it had high success rates.

Answer 5

See the medical link below:

Answer 6

I would like to know myself.
I take Lamictal and Primidone and I still have partial seizures occassionally.

I know there is a surgery they can do.
You would have to speak to your neurlogist.

Answer 7

New Neurons Could Act To Alleviate Epilepsy

The new neurons generated as a result of neural damage due to epilepsy show a reduced excitability that could alleviate the disorder, researchers have found. The researchers said their results suggest that therapies for epilepsy aimed at inducing neurogenesis could prove effective in alleviating the disorder.

In an article in the journal Neuron, published by Cell Press, Olle Lindvall and colleagues at Lund University Hospital and Stem Cell Center described studies in rats examining neurons generated after an epileptic event has been triggered in the animals.

In their experiments, the researchers compared the properties of new neurons generated in rats allowed to exercise by running on a wheel with those in rats in which epileptic seizures were induced by electrical brain stimulation. Specifically, the researchers analyzed the electrical properties of a type of new cells, called granule cells, in the structure called the dentate gyrus of the hippocampus. This structure is known to be a "gate" for propagation of seizures in the hippocampus, a center for learning and memory.

The scientists’ analysis showed that the new neurons in both the runners and the epileptic animals had all the characteristics of mature dentate gyrus cells. However, they found that neurons born into an epileptic environment, compared to the physiological running environment, showed reduced excitatory connectivity to other neurons, as well as increased inhibitory connectivity. Such differences could mean the newly generated neurons "could have significant beneficial effect on the epileptic syndrome," concluded the researchers.

"Our study demonstrates that both a physiological stimulus and an insult to the adult brain trigger the formation of new dentate granule cells, which are functionally integrated into hippocampal neural circuitry," concluded Lindvall and colleagues. They wrote that "following insult, the functional connectivity of new neurons seems to develop in order to mitigate the dysfunction in the epileptic brain. These data provide further evidence for a therapeutic potential of endogenous neurogenesis."


The researchers include Katherine Jakubs, Avtandil Nanobashvili, Sara Bonde, Christine T. Ekdahl, Zaal Kokaia, Merab Kokaia, and Olle Lindvall of Lund University Hospital and Stem Cell Center in Lund, Sweden.

This work was supported by Swedish Research Council, EU project LSHBCT-2003-503005 (EUROSTEMCELL), and Söderberg, Crafoord, and Kock Foundations. Lund Stem Cell Center is supported by a Center of Excellence grant in Life Sciences from Swedish Foundation for Strategic Research.

Jakubs et al.: "Environment Matters: Synaptic Properties of Neurons Born in the Epileptic Adult Brain Develop to Reduce Excitability." Publishing in Neuron 52, 1047-1059, December 21, 2006 DOI 10.1016/j.neuron.2006.11.004. http://www.neuron.org/

What Research Is Being Done on Epilepsy?
While research has led to many advances in understanding and treating epilepsy, there are many unanswered questions about how and why seizures develop, how they can best be treated or prevented, and how they influence other brain activity and brain development. Researchers are studying all of these questions. They also are working to identify and test new drugs and other treatments for epilepsy and to learn how those treatments affect brain activity and development. NINDS’ Epilepsy Therapeutics Research Program studies potential antiepileptic drugs with the goal of enhancing treatment for epilepsy. Since it began in 1975, this program has screened more than 22,000 compounds for their potential as antiepileptic drugs and has contributed to the development of five drugs that are now approved for use in the United States as well as others that are still being developed or tested.

Scientists continue to study how excitatory and inhibitory neurotransmitters interact with brain cells to control nerve firing. They can apply different chemicals to cultures of neurons in laboratory dishes to study how those chemicals influence neuronal activity. They also are studying how glia and other non-neuronal cells in the brain contribute to seizures. This research may lead to new drugs and other new ways of treating seizures.

Researchers also are working to identify genes that may influence epilepsy in some way. Identifying these genes can reveal the underlying chemical processes that influence epilepsy and point to new ways of preventing or treating this disorder. Researchers also can study rats and mice that have missing or abnormal copies of certain genes to determine how these genes affect normal brain development and resistance to damage from disease and other environmental factors. Researchers may soon be able to use devices called gene chips to determine each person’s genetic makeup or to learn which genes are active. This information may allow doctors to prevent epilepsy or to predict which treatments will be most beneficial.

Doctors are now experimenting with several new types of therapies for epilepsy. In one preliminary clinical trial, doctors have begun transplanting fetal pig neurons that produce GABA into the brains of patients to learn whether the cell transplants can help control seizures. Preliminary research suggests that stem cell transplants also may prove beneficial for treating epilepsy. Research showing that the brain undergoes subtle changes prior to a seizure has led to a prototype device that may be able to predict seizures up to 3 minutes before they begin. If this device works, it could greatly reduce the risk of injury from seizures by allowing people to move to a safe area before their seizures start. This type of device also may be hooked up to a treatment pump or other device that will automatically deliver an antiepileptic drug or an electric impulse to forestall the seizures.

Researchers are continually improving MRI and other brain scans. Pre-surgical brain imaging can guide doctors to abnormal brain tissue and away from essential parts of the brain. Researchers also are using brain scans such as magnetoencephalograms (MEG) and magnetic resonance spectroscopy (MRS) to identify and study subtle problems in the brain that cannot otherwise be detected. Their findings may lead to a better understanding of epilepsy and how it can be treated.

Information Resources
BRAIN
P.O. Box 5801
Bethesda, Maryland 20824
800-352-9424
http://www.ninds.nih.gov/

American Epilepsy Society
342 North Main Street
West Hartford, Connecticut 06117
860-586-7505
http://www.aesnet.org/


Citizens United for Research in Epilepsy (CURE)
505 North Lake Shore Drive, #4605
Chicago, Illinois 60611
312-923-9117
312-923-9118 (fax)
[e-mail]
http://www.cureepilepsy.org/



Epilepsy Foundation
4351 Garden City Drive
Suite 500
Landover, Maryland 20785
301-459-3700
800-332-1000
301-577-2684 (fax)
[e-mail]
http://www.epilepsyfoundation.org/

National Association of Epilepsy Centers
5775 Wayzata Boulevard
Suite 200
Minneapolis, Minnesota 55416
952-525-4526


Epilepsy Institute
257 Park Avenue South
New York, NY 10010
212-677-8550
212-677-5825 (fax)
[e-mail]
http://www.epilepsyinstitute.org/

National Organization for Rare Disorders, Inc. (NORD)
55 Kenosia Avenue
P.O. Box 1968
Danbury, CT 06813-1968
[phone]
[phone] (voicemail only)
Fax: [phone]
http://www.rarediseases.org/

National Council on Patient Information and Education
4915 St. Elmo Avenue
Suite 505
Bethesda, Maryland 20814
301-656-8565
301-656-4464 (fax)
[e-mail]
http://www.talkaboutrx.org/

Antiepileptic Drug Pregnancy Registry
Massachusetts General Hospital
Genetics and Teratology Unit
55 Fruit Street
Boston, Massachusetts 02114
888-233-2334
http://www.aedpregnancyregistry.org/

Family Caregiver Alliance
690 Market Street, Suite 600
San Francisco, California 94104
415-434-3388
800-445-8106
415-434-3508 (fax)
[e-mail]
http://www.caregiver.org/

National Family Caregivers Association
10400 Connecticut Avenue
Suite 500
Kensington, Maryland 20895
301-942-6430
800-896-365
301-942-2302 (fax)
[e-mail]
http://www.nfcacares.org/

here are other sites:

New onset Epilepsy
http://aan.com/professionals/practice/pdfs/patient_ep_onset_c.pdf


Refractory Epilepsy
http://aan.com/professionals/practice/pdfs/patient_ep_refract_c.pdf


Treatments for Refractory Epilepsy
http://aan.com/professionals/practice/pdfs/patient_ep_treatment_b.pdf

http://www.webmd.com/content/article/87/99656.htm

http://www.lifestages.com/health/epilepsy.html


good luck!