I'm doing a project on the effects of prescription painkillers and of overdoses of the medicines. Is there a specific way to find out the lethal dose of them? I know for some (like ibuprofen) a specific lethal dose won't be available, but for some (such as acetominphen and codeine), I'm sure there must be a Poison Control database around somewhere.
2006-12-30 08:19:56 · 6 answers · asked by Anonymous in Science & Mathematics ➔ Medicine
I think you should be able to find an LD50 for nearly any compound that is toxic, including most drugs. You might try looking on an MSDS sheet for the compounds.The LD50 is the dosage that kills 50% of the test animals. Don't know whether this is what you're after, but it might help...
2006-12-30 08:27:38 · answer #1 · answered by hcbiochem 7 · 0⤊ 0⤋
Some drugs have an LD50 (a dose that kills half the test subjects) published in their animal studies. It's considered poor form to go around killing people to find out this information, so it's rarely published. With unfortunate experience one gets a vague idea, but individual variations are surprisingly wide, and the number of test subjects on whom reliable information is available is limited. Snatches of information can be found in the PDR and other widely available references as well as in standard toxicology texts, but if you're looking for a simple table you're likely to be disappointed.
2006-12-30 12:08:47 · answer #2 · answered by Anonymous · 0⤊ 0⤋
Methadone is not approved for fibromyalgia. I know, I have fibromyalgia and not only have looked, but have been told what has been approved for fibromyalgia. What can you do? You can call around to find another doctor who would give you methadone for you. Or see if maybe your doctor can give you something else to use instead of methadone for your pain. If you can't or won't do that, the only thing you can really do is take over the counter pain medications such as advil, naproxen, or ibprofen. If you want those pain meds, you have to find someone who would give you those pain meds.
2016-03-29 01:12:13 · answer #3 · answered by Nikki 4 · 0⤊ 0⤋
The amount of a drug that it would take to kill someone varys with the subject. Their height, weight., metabolism, diet, health, and many other variables factor in to how much is lethal....An overdose is simply taking more than is prescribed.....and that is on every bottle.
2006-12-30 08:25:26 · answer #4 · answered by Null 2 · 0⤊ 0⤋
If they die when you give it to the patient... then it was a lethal dose.
2006-12-30 08:29:11 · answer #5 · answered by Joseph K 2 · 0⤊ 0⤋
look them up at the library "Physicians Desk Reference"
2006-12-30 10:36:39 · answer #6 · answered by jimmymae2000 7 · 0⤊ 0⤋