Does it make sense that having an older dad, or mom and dad is related to diabetes 1 w/o family history?

Question

If you have diabetes 1 with no known family history are you the child of a father who was 35 or older?

Bellerophon
I will contact them on my profile it says that e-mails from yahoo answers members are allowed.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15660739&query_hl=8&itool=pubmed_DocSum http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=10333115&query_hl=22&itool=pubmed_docsumhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=10333115&query_hl=22&itool=pubmed_docsum Two of a number of articles linking father's age and risk of diabetes 1.

Answer 1

Your question is not clear; would you care to elaborate?

I would also like to inform you that although I received your e-mail I cannot send a reply to you. There is a problem with the verification of your e-mail so the message cannot be sent.

It is a bug of the system as mentioned in the forum at
http://messages.answers.yahoo.com/next/threadview?m=tm&bn=SEA-YahooAnswers&tid=73425&mid=73582&tof=-1&rt=2&frt=2&off=1

I think you should contact Yahoo Answers Team (or ask for their help through the forum) to fix that problem.
[Edit]
I am not a medical doctor,so I can't give you an exact answer.
As far as I know diabetes type I is an autoimmune disease (your immune system gets a bit crazy, thinks that the cells in your pancreas that produce insulin are "enemy"/foreign cells and starts killing them.
It is a bit tricky dealing with autoimmune diseases since, although they are hereditary, sometimes they need the proper stimulus to be triggered and make their symptoms apparent. For example I know for the irritable bowel syndrom that you might have the genetic predisposition but you might never get an acute crisis (and go to the doctor for it) if there is not a stimulus like stress, depression, some medicine, a drastic change in diet etc. I don't know if something like that could apply for diabetes type I; if so then there could be a "hidden" family history.

If there is truly no family history, then it is possible that this child is the founder of a lineage that will carry the disease but I don't know if it is necessary; I am not sure if all autoimmune illnessess are hereditary. But if such a lineage is established then it means that there is a mutation in the DNA of the parental germ cells. However you won't know if it was the maternal or paternal germ cells or what caused the mutation.
Aging increases the possibility of having mutations but it doesn't mean that it cannot happen at younger ages.
Also having older parents might increase the possibility that the child has a disease because of compromised/mutated DNA in the germ cells but it is not a necessity. So although it could be the reason you cannot pinpoint with certainty age as the source.

Answer 2

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Answer 3

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Answer 4

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