2006-12-20 20:53:57 · 4 answers · asked by Carmz 1 in Health ➔ Diseases & Conditions ➔ Other - Diseases
Circulatory (blood). The overall vascular system is damaged by these fevers.
2006-12-20 21:02:35 · answer #1 · answered by The Invisible Man 6 · 0⤊ 0⤋
The major target organ is the vascular endothelium. Immunologic and inflammatory mediators are thought to play an important role in the pathogenesis of Hemorrhagic Fever Viruses (HFVs). All HFVs can produce thrombocytopenia(decreased platelet), and some also cause platelet dysfunction. Infection with Ebola and Marburg viruses, Rift Valley fever virus, and yellow fever virus causes destruction of infected cells. DIC (Disseminated intravascular coagulation) is characteristic of infection with Filoviridae. Ebola and Marburg viruses may cause a hemorrhagic diathesis and tissue necrosis through direct damage to vascular endothelial cells and platelets with impairment of the microcirculation, as well as cytopathic effects on parenchymal cells, with release of immunologic and inflammatory mediators. Arenaviridae, on the other hand, appear to mediate hemorrhage via the stimulation of inflammatory mediators by macro-phages, thrombocytopenia(low platelet count), and the inhibition of platelet aggregation.
2006-12-21 05:07:35 · answer #2 · answered by coldflesh 3 · 0⤊ 0⤋
Q is which isnt
but ok
in general
chiefly- cardiovascula aand haematinics
2006-12-21 05:12:39 · answer #3 · answered by poison_ivy_sam 4 · 0⤊ 0⤋
The cardiovascular system.
2006-12-21 05:03:09 · answer #4 · answered by jmk 2 · 0⤊ 0⤋