Humalog mix 75/25?

Question

I have been on Humulin R & NPH for many years. My doctor recently switched me to Lantus. I'm having to take 3 to 4 shots daily of Humulin R to bring my sugar down. I'm going to ask my doctor about the Humalog mix. How is the mix working for you?

Thank you both for your advice.I'm really not thrilled about the idea of going on the pump. I honestly don't know if it would be financially possible. I'm very interested in going on Humalog 75/25 or Humalog 50/50 if my doctor will agree. The Lantus is doing nothing at all for me without 3 to 4 shots of Humulin Regular each day. My BS level was 82 this morning. I had a peanut butter sandwich and it jumped to 339 within a few hours. This is with Lantus in my system and without taking any R this morning. I'd rather try the Humalog Mix and take, hopefully, two shots a day. I took 30 units of Lantus last night.

Answer 1

the premixed insulin regimens (like humalog mix) have the advantage of being used only twice daily. They contain a rapid acting insulin (like humalog, and a intermediate acting one, like NPH). the problem is that this regimen is less flexible. It can cause hypoglicemias because the 2 types of insulin add their maximum effect 3 hours after the administration. The dose adjustment is hard too,let's say you have hyperglicemia before dinner.the logic thing to do would be to increase the morning dose, but then a hypoglicemia can occur before noon.
From my experience in diabetes care (5 years only), I can tell that the premixed insulins don't work so good in type 1 diabetes, they should be used for limited time, but many people choose this option because there are only 2 injections, not 4 or 5.

Your doctor (or yourself) have to adjust the dose of Lantus, in order to decrease the need for rapid insulin during the day.
Another option would be replacing humulin R with Humalog. (not humalog mix) This insulin acts faster, you can inject it right before the meal or even right after. Or Apidra .

Answer 2

I have not used either Humulim NPH or R for YEARS and it is very disturbing that these are still in use. Glargine (Lantus) is an excellent replacement for NPH but Regular insulin has been out of date for some time. Both aspart (Novolog) and lispro (Humalog) are true 'rapid' acting insulins. Although Humalog Mix is a good option I would not suggest it until you are at goal with Lantus and Humalog at which point other factors will determine whether or not this is a good option for you and yes it obviously is more convenient. Help your doctor out it sounds as if they need the help!

Answer 3

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Answer 4

If I were you I'd ask if now is the right time to switch to a pump. They take only Humalog (or the equivalent) and you can set a "basal rate" to mimic the slow "rise" your NPH was giving you. For your boluses, pumps usually use a sliding scale similar to what you were bolusing with shots. The nice part is you actually puncture your skin only about once a week, and you'll get less scarring over time.

Right now is DEFINITELY the time to get on a pump, as they are just about ready to roll out the continuous monitoring kind that come with an embedded glucose sensor.

There are legitimate reasons that some people DON'T pump (triathletes, for instance, can't wear a pump in the water), but I strongly encourage you to "take the leap".

Answer 5

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Answer 6

How many day can I keep a pen Humalog Mix 75/25