please tell me as much info you know about pellagra?

Question

im doing a test tomorow and im studding for it can someone please tell me as much info about the desease pellagra i know alot about it but i dont know what part of the experement was an example of good scientific reaserch? thank you!!

Answer 1

Pellagra is a vitamin deficiency disease caused by dietary lack of niacin (vitamin B3) and protein, especially proteins containing the essential amino acid tryptophan. Because tryptophan can be converted into niacin, foods with tryptophan but without niacin, such as milk, prevent pellagra. However, if dietary tryptophan is diverted into protein production, niacin deficiency may still result.

Some sources also claim a relationship between lysine and pellagra, but this position does not have nearly as much support.


Symptoms

The symptoms of pellagra include:

* high sensitivity to sunlight
* aggression
* dermatitis
* red skin lesions
* insomnia
* weakness
* mental confusion
* diarrhea
* dementia (eventually)

The main results of pellagra can easily be remembered as "the four D's": diarrhea, dermatitis, dementia, and death.

Epidemiology

Pellagra can be common in persons who obtain most of their food energy from corn, since untreated corn is a poor source of niacin (vitamin B3). Corn is also a poor source of tryptophan. This disease can be common among people who live in rural South America where corn is a staple. The symptoms usually appear during spring, increase in the summer due to greater sun exposure, and return the following spring. It is also one of several diseases of malnutrition common in Africa, and was endemic in northern Italy, Spain, and southeastern Europe. Alkali treatment of the corn corrects the niacin deficiency, and was a common practice in native American cultures that grew corn. The amino acid deficiency must be balanced by consumption of other sources of protein. It was also common amongst prisoners of Soviet labor camps, the infamous Gulag.
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Answer 2

Chicken Pox!