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how cystic fibrosis is controlled by arecessive gene

2006-11-09 07:20:24 · 5 answers · asked by hansinima 1 in Health Diseases & Conditions Respiratory Diseases

5 answers

I don't understand your use of the word controlled.
If you mean what is the relationship of recessive genes to Cystic Fibrosis?
Because the trait for CF is attached to a recessive gene it means that when that gene is passed on to a child it is harmless on its own. The disease only occurs when one woman with the recessive linked gene mates with a male with the same recessive gene. Two recessives result in the disease happening in the child.
The two parents who only have half the material each on their genes are ''carriers'' of the disease.
Most cystic fibrosis children are blond and blue eyed because these too are thought to be part of recessive genes.
Is that what you want to know?

2006-11-09 07:24:27 · answer #1 · answered by Tempest88 5 · 0 0

The gene involved in cystic fibrosis produces a protein that acts as a tunnel and gate to regulate the passing of chloride ions through the outer membrane of a cell.

In a person with two "normal" copies of this gene, the blueprints to build this tunnel are present on both of the #7 chromosomes.

In a person who is a carrier, one normal gene and one defective gene are present. The defective gene has inaccurate blueprints. Depending upon the exact defect, either a defective tunnel gets built or possibly none at all using these blueprints. But the normal gene still has accurate blueprints for building this tunnel and chloride ions are still able to pass through the cell membrane.

But in a person with two defective copies of this gene, the tunnel cannot be built correctly. Transportation of chloride ions is disrupted and this results in a disease process known as cystic fibrosis.

Since the disease process is avoided with even just one correct copy of the gene, it takes both genes to be bad before a person has CF.

2006-11-11 08:59:25 · answer #2 · answered by Drew 2 · 0 0

a pair of million in 30 persons are vendors of Cystic Fibrosis. As you in all possibility understand, a toddler might desire to inherit a replica of the gene from each parent so as to advance. this suggests the probabilities of having a toddler with cystic fibrosis is 25%. the reality that your first toddler is healthful has no effect of the possibility of having a CF toddler the 2d time around. the possibility keeps to be 25% some human beings might think of this proportion is rather severe and stay away from having toddlers even with the undeniable fact that that is a private selection and you shouldnt rush into any determination like this. Having a toddler with CF is a significant burden, bodily, mentally and emotionally for you and the toddler. even even with the undeniable fact that scientific care is plenty greater effective at the instant there continues to be an significant wellbeing effect on the toddler. not all CF victims are impacted interior an identical way even with the undeniable fact that; for some it is so severe they don't proceed to exist previous infancy, for some they might proceed to exist into adulthood with out even understanding there is something incorrect with them. that is plenty to think of approximately yet once you think of approximately it you do have a seventy 5% possibility of not having a toddler with CF. merely make certain you experience as in case you ought to cope if the toddler become born a sufferer. desire this facilitates.

2016-11-23 13:00:44 · answer #3 · answered by ? 4 · 0 0

All I know is 2 of my cousins died from it and 3 siblings are fine..It hit the first and last child in family but not 3 in middle

2006-11-09 07:23:50 · answer #4 · answered by dwh12345 5 · 0 0

It takes two, just like blue eyes; one from Mom and one from Dad.

See http://www.cff.org/AboutCF/Faqs/ for the answer to this and many other related questions.

2006-11-11 10:35:57 · answer #5 · answered by Picture Taker 7 · 0 0

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