How does Salbutamol work on the bronchial system to relieve the symptoms of asthma?

Answer 1

As with other β2-adrenergic receptor agonists, salbutamol binds to β2-adrenergic receptors with a higher affinity than β1-receptors. In the airway, activation of β2-receptors results in relaxation of bronchial smooth muscle. resulting in a widening of the airway (bronchodilation). Inhaled salbutamol sulfate has a rapid onset of action, providing relief within 5-15 minutes of administration.

In tocolysis, the activation of β2-receptors results in relaxation of uterine smooth muscle, thus delaying labour.
Further info is available at-
http://en.wikipedia.org/wiki/Salbutamol

Answer 2

By sending a message to the muscles which are wrapped around the bronchial tubes and telling them to relax.

In asthmatics these muscles become irritable, "up tight" and they grip the tubes causing wheezing, a tight chest, coughing and shortness of breath.

The main problem in asthma is that there is swelling inside the tubes. It is this swelling that really bugs the muscles so the best treatment is to take a preventer (inhaled steroid-v small dose-) so that the swelling is controlled and the muscles get less annoyed.

Salbutamol should still be used to treat acute symptoms and should always be available

Answer 3

It helps with the opening of the bronchial tubes which close during an asthma attack. It's easier to breathe in when having an attack than to breathe out.

Answer 4

It is a steroid which dilates (opens up and widens) the bronchial passages so that respiration is made easier.
Many people think that asthmatics gasp for breath because they can't breathe in. This is a misnomer, asthmatics have trouble exhaling (breathing out), which means that they can't get rid of carbon dioxide as efficiently as a non-asthmatic person.
When the carbon dioxide builds up, as it's heavier than air, it smothers the oxygen, preventing it from transferring through the lungs and into the blood stream.
The drugs work by opening up the passages allowing more carbon dioxide to be exhaled, which aids the transfer of oxygen and allows easier breathing.

Answer 5

I feel your pain. I've had asthma for 14 years now and have seen several doctors. The truth is, there is no known cure for asthma at the moment. But the symptoms can be prevented. It really depends on what causes your brother's asthma. Mine is usually dust and hot weather. But I think the universal method is using the control inhaler.

I cured my Asthma the natural way?

Answer 6

During an asthma attack, muscles around the airways tighten thus reducing their diameter. This constriction makes it hard to move air in and out of the airways. Salbutamol causes the muscles to relax thus opening up the airways and enabling air to flow.

More specifically, salbutamol falls into the category of medicines known as a short-acting beta 2 agonists. They act on receptors in the lungs called beta 2 receptors. It is the stimulation of these receptors by the agonists that causes the airway muscles to relax and open.

Answer 7

It dilates the bronchial tubes and relaxes the muscles. This encourages easier breathing and allows for better passage of oxygen.

Answer 8

it helps with the opening of the bronchial tubes that get closed during an asthma attack

Answer 9

"The main effect that salbutamol has involves the respiratory system. The muscles that surround the airways relax in response to the hormone adrenaline. Salbutamol is able to mimic adrenaline and bind to these proteins, causing the muscles around the airways to relax. This causes the airways to expand, which makes it easier for air to pass through and get to the lungs."Credits: Livestrong

Answer 10

How Does Salbutamol Work