2006-10-01 04:09:32 · 11 answers · asked by Anonymous in Health ➔ Diseases & Conditions ➔ Heart Diseases
atherosclerotic plaque formation:
excess LDL cholesterol is oxidized by free radicles & then taken up (phagocytosed) by macrophages (tissue monocytes) & transform into faom cells that start secreting substances promoting endothelial cell prolifration (endothelium = cells lining the inside of vesseles).. foam cells accumulate over injured endothelium and form "fatty streaks"..which progress into the atherosclerotic plaque.....
anatomy...there is the left main coronary artery & the right coronary artery..all arising from the ascending aorta..just above the aortic valve...cardiac (heart) perfusion occures during diastole ( heart relaxarion) (not as the rest of the body..during systole ( heart contraction)..
if u want further info on the coronary anatomy..just ask..
2006-10-01 09:28:35 · answer #1 · answered by white skull 3 · 0⤊ 0⤋
The coronary arteries supply blood to the heart so that it can work efficiently. If there is too much cholesterol in the blood plaques are formed in the arteries, causing a blockage often known as a thrombosis. The plaque has a soft centre (lipids) and a harder covering. High blood pressure can damage the covering of the plaque and cause the lipid centre to leak out. When this happens platelets stick to the lipid and form a clot, which blocks the blood vessel. When this happens in the coronary arteries the blood supply to the heart is interrupted. Like the rest of the body the heart needs blood to supply oxygen so that it can work. Without this it will start to die and when this is severe it is known as a myocardial infarction (heart attack). Thrombolysis is fequently used to treat MI and this works by breaking up the clot and restoring the blood flow. However if the ischemia was proonged then the heart tissue can be permenantly damaged, which may lead to heart failure. Angina is similar to MI, although not as severe and sufferers are given Glyceryl Trinitrate (GTN) which causes the blood vessels to dilate and improves blood flow.
2006-10-01 23:19:15 · answer #2 · answered by Anonymous · 0⤊ 0⤋
Why do you expect others to help you with your home work if you do not have the manners to ask for the help in a polite way.
I'm sure this will be deleted but think next time you ask for help.
You have issued a demand not asked a question!!
2006-10-01 04:19:18 · answer #3 · answered by David T 3 · 0⤊ 0⤋
1
2017-03-05 04:39:22 · answer #4 · answered by Mager1964 3 · 0⤊ 0⤋
the arteries that supply blood to the heat which makes it pump so that it can distibute blood throughout the body.
when they are atherosclerotic, they are in the same place but blocked by plaque, which causes difficulty getting blood to the heart and causing a heart attack.
2006-10-01 04:18:29 · answer #5 · answered by sheristeele 4 · 1⤊ 0⤋
Please see the webpages for more details on Coronary arteries, Atherosclerosis and Coronary heart disease.
2006-10-01 04:51:30 · answer #6 · answered by gangadharan nair 7 · 0⤊ 0⤋
Just review the attached site and related links for the information you are looking for:
http://drugcoatedstents.blogspot.com/
2006-10-01 06:56:43 · answer #7 · answered by MADELINE F 1 · 0⤊ 0⤋
why......this is sunday....why the hell should we explain something that happens quite efficiently without us needing to know anyhow.
2006-10-01 04:30:21 · answer #8 · answered by canada grl 4 · 0⤊ 0⤋
Not funny.
This is serious sh*t.
Do your own homework.
2006-10-02 12:59:46 · answer #9 · answered by 34th B.G. - USAAF 7 · 0⤊ 0⤋
No
2006-10-01 04:26:42 · answer #10 · answered by coslindasaid 2 · 0⤊ 0⤋