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please help me with this question.. thank you very much!!

2006-09-24 20:42:51 · 3 answers · asked by me 2 in Health Diseases & Conditions Heart Diseases

3 answers

I did a presentation on the topic last week so:
excess LDL (the bad cholesterol) is oxidized by free radicles & taken up by macrophges (white blood cells) & become "foam cells", these foam cells start secreting substances that promote endothelial cell prolifration (cells lining the vesseles from the inside). foam cells will accumulate on injured endothelium & form "fatty streaks" which will progress into "atherosclerotic plaques"..this will produce the symptomes of angina (heart ischemia). then the disease progress, & platelets are activated, these activated platelets will secrete thromboxan A2 which will promote vasoconstriction (constriction of the artery) & further platelet aggregation. activated plateletes have the gycoprotein 2b/3a receptor which will interact with fibrinogen to form the more stable fibrin...

2006-09-28 07:24:07 · answer #1 · answered by white skull 3 · 0 0

that particular fat is what helps block the arteries. makes it so blood platelets stick in the narrowed area causing a blood clot that causes heart attacks or strokes.

2006-09-24 20:46:44 · answer #2 · answered by Anonymous · 0 0

Please see the webpages for more details on Cholesterol.

2006-09-24 20:59:52 · answer #3 · answered by gangadharan nair 7 · 0 0

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