what is antiphospholipid antibody test?

Question

The answer must consists of the principle of the test and it's relation to Syphilis. It must be related to medical diagnosis of disease.

Answer 1

Antiphospholipid testing is used to help determine the cause of an unexplained thrombotic episode, recurrent fetal loss, thrombocytopenia, and/or a prolonged aPTT test. Depending on the patient’s clinical findings, a physician may order one or more types and classes of these tests to help detect the presence of antiphospholipid antibodies and to help diagnose APS. Cardiolipin antibodies (IgG, IgM, and sometimes IgA) are frequently ordered as they are most common antiphospholipids. If a patient has a prolonged aPTT test, further lupus anticoagulant testing is usually indicated. Anti-beta2 glycoprotein I and anti-phosphatidylserine testing may be ordered along with the other antiphospholipid antibodies to detect their presence and to provide the doctor with additional information.
If an antiphospholipid antibody is detected, the same test(s) may be ordered 8 to 10 weeks later to determine whether their presence is persistent or temporary. If a patient with an autoimmune disorder tests negative for antiphospholipid antibodies, they may be retested as these antibodies may develop later.
Occasionally, antiphospholipid testing may be ordered to help determine the cause of a positive VDRL / RPR test for syphilis. The reagents (chemicals) used to test for syphilis contain phospholipids and can cause a false positive result in patients with antiphospholipid antibodies.
Please note that I am not a medical professional.
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Answer 2

Antiphospholipid testing is used to help determine the cause of an unexplained thrombotic episode, recurrent fetal loss, thrombocytopenia, and/or a prolonged aPTT test. Depending on the patient’s clinical findings, a physician may order one or more types and classes of these tests to help detect the presence of antiphospholipid antibodies and to help diagnose APS. Cardiolipin antibodies (IgG, IgM, and sometimes IgA) are frequently ordered as they are most common antiphospholipids. If a patient has a prolonged aPTT test, further lupus anticoagulant testing is usually indicated. Anti-beta2 glycoprotein I and anti-phosphatidylserine testing may be ordered along with the other antiphospholipid antibodies to detect their presence and to provide the doctor with additional information.
If an antiphospholipid antibody is detected, the same test(s) may be ordered 8 to 10 weeks later to determine whether their presence is persistent or temporary. If a patient with an autoimmune disorder tests negative for antiphospholipid antibodies, they may be retested as these antibodies may develop later.