Beyond Antartica and the ocean's depths, is it possible to tread where no man has before?

Question

And I don't mean space either.

Answer 1

Yes, whereever there are large tracts of forest, desert, or wilderness, there will be places where nobody has trod.

Try Amazon rain forest, Siberian Tundra, Sahara desert.

There will be many mountains in Asia that nobody has climbed. There will be islands in the Pacific that nobody has stepped on.

Answer 2

Lay down a strip of new carpeting and walk on it. You've now trod where no man has before.