Genetic Disorders?

Question

I am doing a science project on Genetic Disorders and I know there are 4 different types of genetic disorders (Single Gene, Multifactorial, Chromosomal & Mitochondrial).
What I need to know is what are some examples of diseases for each of them?

10 points to whoever answers this =]

Answer 1

Very small sample:

Single Gene:
Fragile X
Duchenne Muscular Dystrophy

Multifactoria:
Cancer
heart disease
Alzheimer's disease
arthritis
diabetes
obesity

Chromosomal:
Down syndrome
Klinefelter syndrome
Turner syndrome

Mitochondrial:
LHON (Leber Hereditary Optic Neuropathy)
Kearns-Sayre syndrome
Leigh syndrome

Answer 2

Both records and genuine bodily characteristics provide proof that tendency toward homosexuality ( I say tendency as most contributors consider homosexuality is in a continuum from thoroughly straight to completely homosexual) is either a fabricated from genes or hormone baths that form how the brain developes or a combo of the two. Nonetheless, even if it's absolutely centered on genes, a geneitc sickness is, with the aid of definition, a pathological state. Because it does not necessarily affect a beings vitality or impair any ordinary perform i would say now. Nevertheless, there could also be some that disagree in that it does hinder natural mating. I'd additionally add that many different species even have homosexuals- in that they certainly not mate with the reverse intercourse - might be there's some evolutionary benefit to having homosexuals within the population? We nonetheless don't know. * i would additionally add that despite the fact that we will just about obviously say that now not one 'gene' reasons homosexuality, in many human illnesses a couple of genes come into play making it very hard to pinpoint a genetic purpose. Nevertheless, these are nonetheless genetic problems. Hope this helps!

Answer 3

And example of Single Gene would be Sickle-cell Anemia.

Multifactorial genetic disorder would be something like heart disease, cancer and diabetes.

Chormosomal genetic disorder is Down's Syndrome with an extra 21st chromosome or Klinefelter's syndrome with two X chromosomes and one Y.

A mitochondrial genetic disorder is Leber's Hereditary Optic Neuropathy (LHON) a degeneration of retinal ganglion cells and axons

Answer 4

The gene, SRD5A2, encodes the molecular structure of the isoenzyme 5-alpha-reductase-2. This enzyme, is responsible for the reduction of T, i.e., testosterone, to DHT, i.e., 5-alpha-dihydrotestosterone.

There are many mutations, of this gene, all impairing the effectiveness of 5-alpha-reductase-2. The more severe mutations will result in pseudohermaphrodism, i.e., first trimester, sexual differentiation fails to occur properly. The result is a child, appearing to be a girl, that is genetically a boy. Often, complications arise, with the onset of puberty.

The link below, is to Stanford University Medical Library. You can find more information there. Should you choose to use this site, it may be helpful to search on reviews only. These articles are more comprehensive, and often, they are somewhat tutorial in nature.