Your stomach is a muscular sac located in the upper middle of your abdomen, just below your ribs. The stomach walls are lined with three layers of powerful muscles that mix food with enzymes and acids produced by glands in the stomach's inner lining. Your stomach's delicate tissues are protected from this acidic mix by a thick, jelly-like mucus that coats the stomach lining.
Types of stomach cancer
* Adenocarcinomas. The great majority of stomach cancers are adenocarcinomas, which start in the glandular cells in the stomach's innermost lining. Adenocarcinomas account for about 95 percent of all stomach cancers.
* Lymphomas. These are cancers of immune system tissue in the stomach wall. Some lymphomas are aggressive, whereas others grow much more slowly. The latter, known medically as mucosa-associated lymphoid tissue (MALT) lymphomas, usually stem from H. pylori infection and are often curable when found in the early stages.
* Carcinoid tumors. A small percentage of stomach cancers are carcinoid tumors that originate in the stomach's hormone-producing cells. Carcinoid tumors tend to grow less quickly and spread (metastasize) less frequently than do the more common stomach cancers.
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Gastrointestinal stromal tumors (GISTs). Doctors believe that these rare tumors develop from cells called interstitial cells of Cajal, which are part of your autonomic nervous system. Your autonomic nervous system consists of the nerves that regulate the part of your nervous system that you can't control, such as your heart rate, blood pressure and intestinal function.
Although GISTs can occur anywhere from the esophagus to the rectum, most are found in the stomach. Yet GISTs are not the same as other gastric cancers, differing not only in the cells in which they originate but also in their prognosis and treatment. A majority of GISTs have a specific genetic mutation that allows for treatment with a new form of cancer-specific therapy.
Why stomach cancer develops
Healthy cells grow and divide in an orderly way. This process is controlled by DNA — the genetic material that contains the instructions for every chemical process in your body. Some of the genes in your DNA promote cell division and some slow cell division or program cells to die at the right time. Still other genes control processes that help repair DNA. When DNA is damaged, these genes may not function properly, causing cells to grow out of control and eventually form a tumor — a mass of malignant cells.
Although the causes of many types of cancer aren't clear, researchers have made progress in pinpointing factors that damage DNA in stomach cells and in understanding how that damage leads to cancer. These factors include:
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H. pylori infection. A majority of the world's population is infected with corkscrew-shaped bacteria called Helicobacter pylori (H. pylori) that live deep in the mucous layer that coats the lining of the stomach. Although it's not entirely clear how the bacteria are transmitted, it's likely they spread from person to person through the oral-fecal route or are ingested in contaminated drinking water. H. pylori infection frequently occurs in childhood and can last throughout life if not treated. It's the primary cause of stomach ulcers.
Having ulcers doesn't necessarily put you at higher risk of stomach cancer, but having H. pylori infection does. That's because long-term infection causes inflammation that can lead to precancerous changes in the stomach lining. One of these changes is atrophic gastritis, a condition in which the acid-producing glands are slowly destroyed. It's likely that low acid levels prevent cancer-causing toxins from being properly broken down or flushed out of your stomach.
* Nitrates and nitrites. These are nitrogen-based chemicals that are added to certain foods, especially cured meats such as ham and bacon, hot dogs and deli meats. Both nitrates and nitrites combine with other nitrogen-containing substances in your stomach to form N-nitroso compounds — carcinogens that are known to cause stomach cancer.
* Salted, smoked or pickled foods and red meat. Before the advent of refrigeration, people commonly preserved food by salting, smoking or pickling. But these foods often contain large amounts of nitrites and nitrates, which can be converted in your stomach into cancer-causing compounds. Countries where consumption of salted meat and fish and pickled vegetables is high — Japan and Korea are notable examples — tend to have correspondingly high rates of stomach cancer. Eating a diet high in red meat, especially when the meat is barbecued or well-done, also has been linked to stomach cancer.
* Tobacco and alcohol use. Tobacco use can irritate the stomach lining, which may help explain why smokers have twice the rate of stomach cancer that nonsmokers do. Alcohol has been associated with an increased risk of stomach cancer, but the link between the two isn't clear.-
2007-11-12 20:29:22
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answer #1
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answered by Jayaraman 7
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There are a number of risk factors for stomach cancer, and a lot of the time, just like any cancer, we can't always pinpoint the exact cause. Diet usually does not directly "cause" a cancer, but it can increase your risk. With stomach tumors, dietary risk factors usually include diets that are high in salted, smoked, or pickled foods. That is why stomach cancer is rare in the U.S. but more common in countries with diets high in those types of foods. Other risk factors include inflammation of the stomach, smoking, being a male, having a family history of stomach cancer, or an infection with the bacteria Heliobater Pylori, which is a leading cause of peptic ulcer disease.
Sorry to hear about your friend.
2007-11-12 14:11:46
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answer #2
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answered by Anonymous
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There is no scientific evidence that will prove conclusively that any of these things 'caused' his stomach cancer. Many people eat these things and never get cancer. People who are vegetarians can still get stomach cancer.
Diet had nothing to do with it.
2007-11-12 13:53:21
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answer #3
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answered by Panda 7
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The saturated fats of origin animal, as milk and the red meat are one of the causes. The alcohol and the cigarette promote their development too.
You must consider the following risks factors:
1) Have cases of cancer in my familiar file?
2) I am a person of legal age (>40 years)?
3) Have a life without exercise or sedentary?
4) My feeding is with products process and greasy scrap iron and foods of origin animal?
5) Have a life with the high daily stress, by the work, or my responsibilities?
6) During the day, I am exposed to strong environmental contamination (toxic in the air, water, use of chemistries in the work, etc.)?
7) I expose much to the sun?
8) Drink alcohol and I smoke frequently?
9) Have overweight or Obesity?
10) Have some problem of health like the diabetes, the metabolic syndrome, chronic anemia, undernourishment?
Whenever you respond yes, to anyone of the questions, your risk of this cancer WILL BE MUCH GREATER!
I’m Adviser in Naturist Nutrition.
2007-11-12 13:59:38
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answer #4
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answered by Sonrie 7
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That's called Full-o-crap. High fiber diets are actually proven to reduce GI cancer not promote it.
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2016-04-14 02:28:20
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answer #5
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answered by ? 4
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2017-01-25 14:08:57
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answer #6
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answered by ? 3
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cancer can happen to anyone, life habits often have a contributing factor but dont necessarily always cause it.
2007-11-12 12:41:52
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answer #7
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answered by chris m 4
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