What happens when the creatinine level in blood increases?

Answer 1

Creatinine is a chemical waste molecule filtered and disposed by the kidneys. Increasing blood level indicates problem in kidney functions.

So what happens when creatinine level increases? Aside from an indication that it signals alteration in kidney functions,high levels of creatinine at the same time can also break down the kidneys and liver and it can also cause an electrolyte imbalance.

As its level rises, it means the kidney function diminishes which will also have trouble with the rest of its vital functions. Surely, BUN will also rise, and everything will be in trouble. The sequence of the effects would then involve the entire body system which ultimately could become fatal and lead to death in case the kidney function is in failure.

Answer 2

I suppose that the most common reasons for developing raised creatinine levels will be when the filtration mechanism becomes gradually damaged by long-term hypertension or diabetes.

In any severe feverish illness where the person gets dehydrated, there may be a rise in blood creatinine levels as the kidney tries to deal with the breakdown products of proteins in our bodies. Acute renal failure may result from trauma, blood loss, serious infections, poisons, some cancers and biochemical imbalances, to name but a few causes.

As the kidneys become increasingly unable to cope, so the creatinine level rises. A reliable measure of renal function is often expressed to doctors by a creatinine clearance test. This involves a formula that expresses the blood creatinine in relation to the amount of creatinine produced in the urine over a 24hour interval.

On its own, a single creatinine level does not really give us much useful information. It is more valuable to look at a few other tests at the same time, including urine examination for biochemistry and microbiological content, together with X-rays or scans, and sometimes even biopsies of the kidneys. But, in very general terms, a rising level of creatinine signifies an increasing problem with poorly performing kidneys.

Neither creatinine nor urea is directly toxic - these are just substances used to measure kidney function.

Answer 3

Creatinine Levels

Answer 4

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Answer 5

Since we don't make inulin (NOT Insulin), creatinine level and creatinine clearance is a very convenient measure of how well the kidneys are working or not carrying out their function. As the serum creatinine rises, this is an indicator that this molecule is not being cleared by the kidneys at an optimal rate. Of course, we always evaluate the Cr in the context of hydration status, BUN, etc. But I hope that this very simplistic answer suffices.

Answer 6

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Creatinine is a breakdown product of muscle. This happens normally to people every day as part of normal muscle use. The kidneys are responsible to clear creatinine form the blood. Unless there is a very recent reason your brother has had some form of muscle damage, then he may have kidney problems. He must have seen a doctor to get the blood test, so make sure he follows up and gets treated if there is a problem.

Answer 7

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Answer 8

It means your kidneys is f---ed.
We see elevated creatinine levels in lots of conditions:
Acute tubular necrosis
Dehydration
Diabetic nephropathy
Eclampsia
Glomerulonephritis
Muscular dystrophy
Pre-eclampsia
Pyelonephritis
Reduced renal blood flow
Renal failure
Rhabdomyolysis
Urinary tract obstruction

Answer 9

Avoid Kidney Failure Dialysis Naturally - http://Kidney.NaturallyGo.com

Answer 10

Creatine* and weight gain with water, energy and strength increase