I am interested in the particular mechanism that causes itchiness in an allergic reaction. I am aware that a Type I hypersensitivity reaction (ie. allergic reaction) is due to mast cell degranulation causing histamine release. I am looking for the steps that follow leading to the itchiness (ie. proteins, receptors...) and any biological reason/advantage for this. Thanks!
2007-11-02 09:09:06 · 2 answers · asked by Anonymous in Science & Mathematics ➔ Medicine
OK, the steps that follows:
>>Following the histamine release,it leaks into the surrounding tissues.
>>Histamine then causes "itch sensation" which sensation is received by "itch receptors" and transmitted through slow-conducting unmyelinated C-polymodal and possibly type A delta nociceptive neurons with free nerve endings found near to the dermal- epidermal junction.
>>The sensation is transmitted to the central nervous system as itchiness.
>>As a quick response of motor transmission, the tendency is to rub or scratch the itchiness.
>>In allergic reactions,histamine causes inflammation, redness (erythema) and itching (pruritis) on the skin surface as an immune defense mechanism. It is an alarm that body's systems are so overloaded with toxicity.
2007-11-02 11:43:24 · answer #1 · answered by ♥ lani s 7 · 1⤊ 0⤋
It's an allergy to apples and some fruits because you're allergic to pollen and the peel of the fruit are mistaken as pollen and allergic reactions can start i have the same problem try peeling the fruit.
2016-04-02 01:03:35 · answer #2 · answered by Anonymous · 0⤊ 0⤋