Vitamin B12 or cyancobolamin deficiency :
Symptoms of severe vitamin B12 deficiency (regardless of the cause) may include burning of the tongue, fatigue, weakness, loss of appetite, intermittent constipation and diarrhea, abdominal pain, weight loss, menstrual symptoms, psychological symptoms, and nervous system problems, such as numbness and tingling in the feet and hands. Most symptoms can occur before the deficiency is severe enough to cause anemia. Depression . Signs and symptoms of Pernicous anemia Healthcare professionals have a series of laboratory tests that can determine B12 deficiency at earlier stages that are not accompanied by anemia
In a person with true PA, initial B12 supplementation should begin with an injection given by a qualified healthcare professional. After blood abnormalities are reversed, maintenance supplementation can be successfully accomplished with oral vitamin B12 at 1,000 to 2,000 mcg (1 to 2 mg) per day and does not require further injections.7 In a person lacking intrinsic factor, only about 1% of this oral amount (10–20 mcg) will be absorbed, but that amount is more than sufficient to prevent future vitamin B12 deficiency. Many physicians are unaware of this well-researched option and thus unnecessarily recommend lifelong B12 injections.
People with a vitamin B12 deficiency due to a malabsorption condition must have an appropriate treatment tailored to their individual needs by a healthcare professional. In older people who have inadequate absorption of vitamin B12 from food due to low stomach acid, prevention of deficiency can be achieved with small amounts of supplemental vitamin B12 found in B-complex and multivitamins. However, if a deficiency already exists in such people, a vitamin B12 injection is typically the initial treatment, followed by varying amounts of oral supplemental vitamin B12 depending on the extent of the deficiency
Individuals with vitamin B12 deficiency must not take large amounts (greater than 800 mcg per day) of folic acid without the supervision of a doctor. At high levels, folic acid can mask the signs of vitamin B12 deficiency, potentially resulting in serious and irreversible nerve damage.
The Food and Nutrition Board of the Institute of Medicine of the National Academy of Sciences has recommended the following Dietary Reference Intakes (RDI) for vitamin B12:
Infants Adequate Intakes (AI)
0 through 6 months 0.4 micrograms/day ~ 0.05 micrograms/Kg
7 through 12 months 0.5 micrograms/day ~ 0.05 micrograms/Kg
Children Recommended Dietary Allowance (RDA)
1 through 3 years 0.9 micrograms/day
4 through 8 years 1.2 micrograms/day
Boys
9 through 13 years 1.8 micrograms/day
14 through 18 years 2.4 micrograms/day
Girls
9 through 13 years 1.8 micrograms/day
14 through 18 years 2.4 micrograms/day
Men
19 years and older 2.4 micrograms/day
Women
19 years and older 2.4 micrograms/day
Pregnancy
14 through 50 years 2.6 micrograms/day
Lactation
14 through 50 years 2.8 micrograms/day
2007-10-20 10:53:55
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answer #1
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answered by rosieC 7
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Are we talking about pernicious anemia? Usually characterized by a red, beefy looking tongue. The treatment is B-12 injections monthly for the rest of your life.
2007-10-20 09:56:08
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answer #2
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answered by Nurse Brandi 4
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