what is the relationship of red blood cells production to bone marrow cancer?

Question

about leukemia, erythroleukemia

Answer 1

Leukemia is cancer of your body's blood-forming tissues, including the bone marrow and lymphatic system. The word "leukemia" means "white blood" in Greek. The disease usually starts in the white blood cells.

Under normal circumstances, your white blood cells are potent infection fighters. These cells normally grow and divide in an orderly, controlled way, as your body needs them. But leukemia disrupts this process.

In leukemia, your bone marrow produces a large number of abnormal white blood cells. They look different from normal blood cells and don't function properly. Eventually, they block production of normal white blood cells, impairing your ability to fight off infection. Leukemia cells also crowd out other types of blood cells produced by the bone marrow, including red blood cells, which carry oxygen to tissues throughout your body, and platelets, which help form blood clots.-

Answer 2

Erythroleulemia is a very rare form of Acute Myloid Leukaemia. Most leukaemia's effects just the white cell production in the bone marrow. In the case there is an over production of the red blood cells in the blood of which are immiture and dont work as they should. eg. transporting oxygen around the body.

Answer 3

Bone Marrow makes the RBC's and if the Marrow is damaged in some way then RBC's can't be made properly. In turn you have less blood running through your body and less oxygen to your organs.

Answer 4

Bone Marrow Transplant
Surgery

MORE INFORMATION




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Formed elements of blood


Bone-marrow transplant - series

Definition
A bone marrow transplant is a procedure that transplant healthy bone marrow into a patient whose bone marrow is not working properly. A bone marrow transplant may be done for several conditions including hereditary blood diseases, hereditary metabolic diseases, hereditary immune deficiencies, and various forms of cancer.

The healthy bone marrow may be taken from the patient prior to chemotherapy or radiation treatment (autograft), or it may be taken from a donor (allograft).



Alternative Names
Transplant - bone marrow

Description
Bone marrow is a soft, fatty tissue inside the bones. This is where blood cells (red blood cells, platelets, and white blood cells) are produced, and where they develop. In a disease of the blood cells -- especially cancers such as leukemia -- high doses of chemotherapy may be required to destroy the cancer. However, this also destroys normal blood cells.

In other cases in which hereditary or acquired disorders cause abnormal blood cell production, transplantation of healthy bone marrow may correct these problems. Transplanted bone marrow will restore production of white blood cells, red blood cells, and platelets.

Bone marrow transplant patients are usually treated in specialized centers. The patient stays in a special nursing unit -- a bone marrow transplant unit, or BMT -- to limit exposure to infections.

Donated bone marrow must match the patient's tissue type. It can be taken from the patient, a living relative (usually a brother or a sister), or from an unrelated donor (found through the national marrow donor program). Donors are matched through special blood tests called HLA tissue typing. (See HLA antigens .)

Bone marrow is taken from the donor in the operating room while the donor is unconscious and pain-free (under general anesthesia). Some of the donor's bone marrow is removed from the top of the hip bone. The bone marrow is filtered, treated, and transplanted immediately or frozen and stored for later use. Transplant marrow is transfused into the patient through a vein (IV) and is naturally carried into the bone cavities where it grows to replace the old bone marrow.

Alternatively, blood cell precursors, called stem cells, can be made to move from the bone marrow to the blood stream using special medications. These stem cells can then be taken from the bloodstream through a procedure called leukapheresis.


Acute Myelogenous LeukemiaAcute Myeloid Leukemia (AML) is a type of cancer in which the bone marrow makes abnormal myeloblasts (a type of white blood cell), red blood cells, or platelets.

Acute Myeloid Leukemia (AML) is a cancer of the blood and bone marrow. This type of cancer usually gets worse quickly if it is not treated. It is the most common type of acute leukemia in adults. AML is also called acute myelogenous leukemia, acute myeloblastic leukemia, acute granulocytic leukemia, and acute nonlymphocytic leukemia.

Normally, the bone marrow produces stem cells (immature cells) that develop into mature blood cells. There are 3 types of mature blood cells:

Red blood cells that carry oxygen and other materials to all tissues of the body.
White blood cells that fight infection and disease.
Platelets that help prevent bleeding by causing blood clots to form.
In AML, the stem cells usually develop into a type of immature white blood cell called myeloblasts (or blasts). The myeloblasts in AML are abnormal and do not mature into healthy white blood cells. Sometimes in AML, too many stem cells develop into abnormal red blood cells or platelets. These abnormal white blood cells, red blood cells, or platelets are also called leukemia cells or blasts. Leukemia cells are unable to do their usual work and can build up in the bone marrow and blood so there is less room for healthy white blood cells, red blood cells, and platelets. When this happens, infection, anemia, or easy bleeding may occur. The leukemia cells can spread outside the blood to other parts of the body, including the central nervous system (brain and spinal cord), skin, and gums.