Anyone took Glucophage for fertility treatment?

Question

The doctor prescribed Glucophage so I would ovulate and hopefully get pregnant. I'm confused as of how does it actually work and how effective is it?

I'm not diabetic, but have a very mild case of polycystic ovaries syndrome and I'm a bit overweight. The doctor said that if I lost weight and took Glucophage (500mg twice a day) I should get pregnant.

Anyone with some kind of experience with Glucophage, please share!

Thanks!

Answer 1

I have a support group for women with PCOS and endo. We have alot of information posted on our website(including information about metformin and why it is used for PCOS) that can answer all your questions and get the support you need.
Please join us.

we are located at:

http://www.cafemom.com/group/endosupport

Hope to see you there





Here is some info about metformin for you:


Metformin is currently being used to induce ovulation in women with polycystic ovarian syndrome (PCOS). Metformin is an insulin sensitizing drug originally used in the treatment of diabetes. Metformin “reverses” insulin resistance (hyperinsulinemia) thus effectively treating many diabetics.


Up to 40- 70% of patients with PCOS have hyperinsulinemia which leads to excess androgen (male hormones) production by the ovaries and increased production of LH by the pituitary. The body tries to compensate for insulin resistance by the “over production” of insulin. Increased LH levels cause further elevations in androgens. Clinically, this results in ovulatory irregularities (or anovulation), increased body hair, numerous small ovarian cysts, and a classic “pear shaped” body appearance (obesity; although not always) and long term negative health consequences such as diabetes.


Metformin sensitizes the cells to insulin thus lowering the body's production of insulin and consequently reducing androgen production. Once androgen production has been normalized ovulation can often resume. Metformin is dosed at 500 mg three times per day and Clomid or FSH may be added if ovulation is not established.

Answer 2

I did four cycles of clomid because I used to be anovulatory. I ovulated whenever on 50 mg days 5-9. Since I didn't get pregnant my obgyn despatched me to the RE. (his title is Dr. Kiltz with the CNY fertility middle). When I went they did a SA on my dh and determined that he had a high-quality rely (155 million) and first-class motility so it used to be most likely my quandary. The doc did a trans-vaginal ultrasound and determined i have pcos. I've it mildly though due to the fact the only indicators of it's not ovulating and the U.S.And i don't have got to take metformin. I weigh 126 pounds and i'm 5'5". I will have my hsg carried out this month also. The doc stated for the reason that I used to be already ovulating utilizing clomid, he used to be going to provide me clomid again but this time do an Ovidrel trigger shot to make me O after which an IUI tomorrow. He mentioned he'll do this for two cycles and if i'm still not pregnant he's going to do 4 extra cycles using injectables and IUI. If that doesn't work then we can transfer to IVF. My insurance covers IUI for 6 cycles along with the meds. Once we move to IVF (god forbid) they is not going to duvet something. I suppose you have to ask your doc about establishing another therapies equivalent to IUI. I've heard that dropping pounds with pcos may also be fairly hard I wish you good fortune. I'm hoping you get someplace along with your doc.

Answer 3

I have been on glucophage for the past month, and am in the same boat as you (PCOS and slightly overweight.) In my case, I was put on it to try and regulate my insulin resistance associated with PCOS, and to balance me out, so that I begin to have a regular cycle, thus increasing my chances of conceiving.

Answer 4

hey I hear it does work, just have faith, I am currently on it and I have pcos this is my 1st month on it, it seems to be working because I had a real short period whicih I haven't had a years, I am taking 500mg twice a day also, I did 3 cycle of clomid without any success, I am now taking clomid 100mg (3-7) with metformin, if it doesn't work this month I'll be taking injectables, I have a dr appointment on Friday, if metformin works for me I'll keep u in touch, but every woman is different some will conceive some wouldn't

Answer 5

Yep.

I took it for 3 months and got pregnant.
I now have beautiful 6 month old baby girl.


Check out the website below for more info on your PCOS and message boards.

Good luck.