what are the causes of hypocalcemia and its rationale?

Question

pls. help me... thank you

Answer 1

lack of calcium

Answer 2

Hypocalcemia (Low Calcium)


What is Hypocalcemia?

Hypocalcemia is an electrolyte imbalance and is indicated by a low level of calcium in the blood. The normal adult value for calcium is 4.5-5.5 mEq/L.


Calcium is important for healthy bones and teeth, as well as for normal muscle and nerve function. Normal blood calcium levels are maintained through the actions of parathyroid hormone (PTH), your kidneys and intestines.

If your blood test results show hypocalcemia, your doctor may check your albumin level as well. If your albumin is low, your calcium level should be corrected for this. A corrected calcium level will be higher if the albumin is low.

What Causes Hypocalcemia?

There are many causes of hypocalcemia, these include;

Vitamin D deficiency
Chronic renal failure
Magnesium deficiency
Alcoholism
Biphosphonate therapy - drugs used to treat high blood calcium levels or pills used to treat osteoporosis.
Certain types of leukemia or blood disorders
A complication of chemotherapy, tumor lysis syndrome, occurs when your body breaks down tumor cells rapidly, after chemotherapy. This may cause hypocalcemia, high blood potassium levels, and other electrolyte abnormalities. This is very serious, and if your blood test results indicate you suffer from it, your doctor or health care provider will need to closely monitor you during this time.
Drugs such as diuretics, estrogens replacement therapy, fluorides, glucose, insulin, excessive laxative use, and magnesium may also lead to hypocalcemia.
Certain things in your diet, like caffeine, phosphates (found in soda pop), and certain antibiotics may make it difficult for you to absorb calcium.
Vitamin D, however, helps you to absorb calcium in your body
as Vit D is( sych as from the sunshine )is needed for synthesis or proper absorption of calcium by the body.

Answer 3

Calcium regulation is critical for normal cell function, neural transmission, membrane stability, bone structure, blood coagulation, and intracellular signaling. The essential functions of this divalent cation continue to be elucidated, particularly in head injury/stroke and cardiopulmonary effects. Depending on the cause, unrecognized or poorly treated hypocalcemic emergencies can lead to significant morbidity or death.
Pathophysiology
Metabolic and endocrine emergencies require an understanding of normal physiology.
Calcium regulation is maintained by parathyroid hormone (PTH), vitamin D, and calcitonin through complex feedback loops. These compounds act primarily at bone, renal, and GI sites. Calcium also is affected by magnesium and phosphorus.

Answer 4

Lack of calcium and/or vitamin D. The body needs calcium for bone growth and general function. But the body needs vitamin D (which you can get from sunlight) to absorb the calcium from the blood.