Pref in ug DNA per Litre?
Thank you
2007-09-14 22:59:19 · 2 answers · asked by kttiptop 2 in Science & Mathematics ➔ Medicine
Some scientist have proposed that some neoplastic disorders might be diagnosed earlier if they can find an elevation of extracellular DNA in plasma/serum. This would be cut-up pieces of dna or plasmids and not genetic nuclear dna as we would normally think of it.
As far as I could find they are still trying to find out what an average level in μg per litre would be.
ref: http://www.publications.parliament.uk/pa/cm200506/cmhansrd/cm060522/text/60522w0060.htm
"No estimates have been made of the average levels in the United Kingdom population of free cell deoxyribonucleic acid (DNA) in microgram DNA per litre of plasma..."
2007-09-15 01:17:06 · answer #1 · answered by Long Tooth 6 · 0⤊ 0⤋
there shouldn't be any free-floating dna in plasma. dna is actually fairly unstable outside of a cell and gets rapidly broken down by enzymes in the blood. if there are viruses present in the bloodstream, then i suppose that could qualify as "cell-free dna" but again, that wouldn't be found normally in the bloodstream.
2007-09-14 23:38:30 · answer #2 · answered by belfus 6 · 1⤊ 0⤋