HELP - What do these bloodwork results mean? HIGH white blood cells, platelets, neutrophils, and lymphocytes.?

Question

I have EVERY symptom of Lupus. My doc sent me for bloodwork and had an ANA test done to see if I have Lupus. The ANA came back negative. However, for OVER A YEAR NOW, my white blood cell count has been high (13.3), my platelets have been high (416), my spleen, liver and left kidney have been swollen (ultrasound), and I have had a LOT of pain under my rib cage on both sides, especially my left side. If I stand or sit for too long, my stomach bloats out (esp when standing). The doctors around here don't seem too concerned about the constant pain I'm in, which has made me lose even MORE faith in doctors. Someone please help me!

My bloodwork results are as follows:
White blood cell (13.3)
Red blood cell (4.43)
Hemoglobin (14.4)
Hematocrit (42.7)
MCV (96.4)
MCH (32.6)
MCHC (33.8)
RDW (12.8)
Platelet (416)
Absolute Neutrophils (8326) - 62.6%
Absolute Lymphocytes (3963) - 29.8%
" Monocytes (705) - 5.3%
" Eosinophils (266) - 2%
" Basophils (40) - 0.3%
ANA - neg
HgA1C - 5.0

Answer 1

For those with systemic lupus erythematosus the symptoms are as follows: 95% have joint pain, 90% have a fever of greater than 100 degrees, 90% have arthritis/swollen joints, 81% have extreme fatigue, 42% have the classic butterfly rash or discoid rash, 74% have body rashes, 71% have anemia, 50% have kidney involvement, 45% have chest pain on deep breathing or have pleurisy, 30% are sun or light sensitive, 27% have hair loss, 20% have abnormal blood clotting, 17% have Raynaud's phenomenon, 15% have seizures and 12% have aphthous (mouth) ulcers. Those with SLE can also have pericarditis. The white blood cell count will usually be decreased. Yours is slightly elevated. You say you have all the symptoms. Do you really?

I've reviewed your blood work. Your WBCs are, as I said, a little high but certainly not alarmingly so. The high end of normal is 10. Levels can be elevated due to stress, smoking, medications, infection, tissue necrosis, collagen disease, histamines, cancer and certain anemias.

Your basophils are slightly decreased. The range is 0.4-1.0. 0.3 isn't alarming. Can be due to stress, hypersensitivity reactions and pregnancy. MCH is mean corpuscular hemoglobin and is a measurement of the weight of your RBCs. Yours is slightly elevated and this can be due to macrocytic anemias. Your platelets are also slightly elevated. The range is 150-400. This can be due to infections, acute blood loss, splenectomy, polycythemia vera and myeloproliferative disease.

The rest of your values are completely within normal limits. One caution, the conditions that can cause abnormal values do not necessarily apply to you. These must be looked at as a total picture and taken into consideration with other diagnostic test results and can't be considered individually. By this I mean that, for instance, your platelet & WBC counts don't mean you have both cancer and ploycythemia vera. T

I don't know how large your internal organs are, how much outside the norm. An enlarged spleen and liver can certainly cause pain and these, along with an enlarged left kidney, are signs of an underlying problem. Have you had a urinalysis, urine culture and sensitivity, renal and liver function tests to rule out disease or infection of these areas? A nuclear spleen scan? Have any GI diagnostics been done?

Have you insisted that attention be paid to your pain? Have you stressed the pain you're having? Are you walking away from appointments without having your pain addressed?

I'm just not convinced, based on what information you've provided, that SLE is the cause and I think you're looking in the wrong direction. Without more diagnostics, I can't even speculate on what the underlying problem may be. But please be assertive about further tests and pain management. If you can, let me know how this progresses.

Answer 2

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Answer 3

Hi, im Chris, I do have Lupus. I really liked Tweetybirds answer. Everything in your labwork may be slightly elevated, but not signifigantly. All or some can be due to infection, even clogged bile ducts of Liver. Or kidney stones, or some issue with your pancrease. The one thing I canm think of, is there are no liver tests listed, nor kidney tests....but yet you are having the same symptoms I have with my autoimmune hepatitis. within a physical test and ultra sound, upon seeing swollen liver, kidneyes, et all, they would do all those tests, possibly even biopsies. Sounds like you can have MONO . and having the physical symptoms of Lupus, dosnt make up the 4 of 11 critera. which many of the symptoms are not part of. On the other hand, my ANA is funky. It can be Positive one day, and negative the next.

Somthing is up, but what? It can be hundrads of things, autoimmune, viral, bacterial

here is the Real Lupus diagnostic critera, there is a difference between a symptom, and critera.

Diagnostic criteria for lupus
Provided by:
Last Updated: June 29, 2004
Diagnostic criteria for lupus
The following criteria are used to distinguish lupus (systemic lupus erythematosus, or SLE) from other autoimmune and rheumatic diseases.

A person with 4 of these 11 conditions can be diagnosed with lupus; 3 symptoms suggest that lupus is probably present, and 2 raise the possibility of lupus. Symptoms may be present all at once or appear in succession over a period of time. 1

Butterfly (malar) rash on cheeks
Rash on face, arms, neck, torso (discoid rash)
Skin rashes that result from exposure to sunlight or ultraviolet light (photosensitivity)
Mouth or nasal ulcers, usually painless
Joint swelling, stiffness, pain involving two or more joints (arthritis)
Inflammation of the membranes surrounding the lungs (pleuritis) or heart (pericarditis). This inflammation is called serositis.
Abnormalities in urine, such as increased protein or clumps of red blood cells or kidney cells, called cell casts, in the urine
Nervous system problems, such as seizures or psychosis, without known cause
Problems with the blood, such as reduced numbers of red blood cells (anemia), platelets, or white blood cells
Positive antinuclear antibody (ANA) test
Signs of increased autoimmunity (antibodies against normal tissue), as shown by laboratory tests

Theres always an answer to the riddle
Chris

Answer 4

Those are very non-specific findings. You may need to have a heart-to-heart with your doctors about pain management. You should keep a few things in mind while you're at it, though: it isn't at all unusual to be unable to come up with a definitive diagnosis of rheumatologic diseases for two and even three years. The science is just not there yet. And what you interpret as a lack of concern may in large part be because they're doing their job. You're focused (understandably) on the pain. They're obliged to consider whether their treatments of the pain mightn't do more harm than good, and that's both complicated and an area where you might be grateful for their ability to be objective in their assessments.

Answer 5

Lupus White Blood Cells

Answer 6

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Best

Answer 7

Elevated Wbc And Platelets

Answer 8

It suggests an infection with Gram+ve bacteria(most often).If you are otherwise healthy,but slightly indisposed use an antibiotic chosen by your doctor.This cell count becomes normal after a while.

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Answer 9

Without looking things up, a high white cell count indicates infection.

Answer 10

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