You are correct in saying that cancer is caused by errors in gene expression. To go a little more in depth most cancers are caused by errors in the genes that control cell division. There are two types of genes that control cell division.
The first one of them is the normal gene that tells a cell when to divide, this is called the RAS gene. If there is an error in this gene and it gets stuck in an ON position then cells replicate out of control and you get cancer.
There is a gene called the p53 tumor suppressor gene. Its job is to stop cell division in cells that have errors in them. p53 tells cells to die if they have errors that cannot be repaired. If the p53 gene gets broken, stuck in the off position, or lost from the genome, it can help contribute to formation of a cancer. An error in the p53 gene alone does not cause cancer as cells that have minor errors do not have to cause major issues within the body. However if a cell has an error in p53 then it has another error in RAS, then you have a cancer cell. This is because without RAS the cell will divide uncontrollably and without p53 the cell's division cannot be stopped even though it has an error.
Most cancer treatments involve chemotherapy drugs or radiation that are toxic to your cells and to cancer cells. The reason that chemotherapy drugs and radiation work is that cancer cells are dividing much faster than normal and are more susceptible to the drugs effects.
If you manage to kill all of the cancer cells then you are considered "cured." However this is not always easy which is why cancer patients still die sometimes even when they are treated and why sometimes cancers come back.
I tried to give you a little deeper explanation without being to confusing. I've attached articles if you'd like to know more. I hope this helps.
2007-09-05 15:01:58
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answer #1
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answered by VA_Surgeon 5
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There are hundreds of different genes that can be involved in the carcinogenesis process. Additionally, there are dozens of different mechanisms by which any one of these genes can have its expression modified. Consequently, the genetic basis of the hundreds of different forms of cancer is a very complicated process. The process is so complicated that it is now estimated that no two cancers (of the millions diagnosed every year) have the exact same genetic variations. Simply, no two cancers are the same - each one is genetically different.
2007-09-06 01:46:55
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answer #2
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answered by Doctor J 7
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if that were the only way cancer was caused then I suspect researchers would find an answer fairly quickly, but it isn't. And cancers mutate and change, and there are multiple kinds. So many diseases fall under the label "Cancer", I doubt there will ever be a "cure for Cancer" there are too many of them.
2007-09-05 21:42:34
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answer #3
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answered by essentiallysolo 7
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