Why does smoking increase the risk of bladder cancer?

Question

It seemd obvious why it would cause lung ca, oesphageal ca, and oral cavity ca, but why bladder ca?

Is there a particular carcinogen responsible or reason why it causes transitional cell carcinoma of the bladder?

Answer 1

Smoking is considered one of the greatest risk factors for bladder cancer. The risk is probably due to the fact that cancer-promoting substances found in tobacco tend to collect in the urine, and then become concentrated in the bladder while awaiting excretion. Other chemicals, including aniline dyes, beta-napthylamine, benzadine salts, and mixtures of aromatic hydrocarbons also are believed to be cancer-causing agents. These chemicals are widely used in the rubber, leather, textile, chemical, plastics, petroleum,
wood, and paint industries. It may take up to 50 years after the original chemical exposure for bladder cancer to develop. -

Answer 2

The greatest risk factor for bladder cancer is smoking. Smokers are more than twice as likely to get bladder cancer as nonsmokers.

Some of the carcinogens (cancer-causing chemicals) in tobacco smoke are absorbed from the lungs and get into the blood. From the blood, they are filtered by the kidneys and concentrated in the urine. These chemicals in the urine damage the urothelial cells that line the inside of the bladder. This damage increases the chance of cancer developing.

I hope that you got the idea..

Answer 3

Smoking inserts hundreds of carcinogenic substances into the body as a whole, increasing cancer risks in general, not just the localised sites you mention. Transitional cell cancer is the type the bladder is most prone to anyway, it makes up 90% of all bladder cancers.

Answer 4

Exposure to environmental carcinogens of various types is responsible for the development of most bladder cancers. Tobacco use (specifically cigarette smoking) is thought to cause 50% of bladder cancers discovered in male patients and 30% of those found in female patients. Thirty percent of bladder tumors probably result from occupational exposure in the workplace to carcinogens such as benzidine. Certain drugs such as cyclophosphamide and phenacetin are known to predispose to bladder TCC. Chronic bladder irritation (infection, bladder stones, catheters, bilharzia) predisposes to squamous cell carcinoma of the bladder. Approximately 20% of bladder cancers occur in patients without predisposing risk factors. Bladder cancer is not currently believed to be heritable (i.e., does not "run in families" as a consequence of a specific genetic abnormality).
Please see the web pages for more details on Bladder cancer.

Answer 5

Tobacco smoke contains over 4000 chemicals, 60 of them are KNOWN carcinogens (things that increase teh risk of cancer).

These spread everywhere in your body, as they can be absorbed by the blood in the lungs, and increase the risk of a wide variety of cancers, including bladder cancer.

Answer 6

Yes it does cause bladder cancer because your kidneys filter all the stuff you inhale that enters into your blood system through your lungs and when the kidneys filter out and send it to your bladder the tubes that connect the bladder and the kidneys always empty out into the same spot and it has been proven that years of these chemicals hitting the same spot causes bladder cancer

Answer 7

Because your lungs are connected to your circulatory system. You breathe in these cancer-causing compounds from cigarette smoke. Your body takes what you are normally supposed to breathe (oxygen) and delivers it to your tissues. So in addition to delivering oxygen to your tissues (via your blood) it delivers the carcinogens as well. Make sense??

Answer 8

Yes. Smoking will leads to lungs disease. Pls visit this website this more helpful to u.

Answer 9

well ive never heard it causes that. that is a new one on me.