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Hi,
What is stronger, 20mg of methadone or a 20mg Kadian capsule? (Kadian is supposed to be some kind of Morphine time release capsule)
If someone is used to taking 100mg of Methadone per day, then will a 20mg Kadian capsule, even crushed up, have any noticable effect on that person that is used to taking 100mg of methadone every day?
Would the 20mg Kadian have a stronger effect than 20 mg of Methadone if I was to crush up the Kadian medicine so it will absorb all at once? Or is methadone so much stronger that not even crushing the Kadian will make it the same as methadone?
Thank you

2007-08-17 11:50:24 · 3 answers · asked by perryinjax 3 in Science & Mathematics Medicine

3 answers

It's complicated on a number of points, so I wouldn't advise a simple substitution. Roughly (very roughly) two thirds of morphine is "lost" to first-pass metabolism through the liver when taken orally, so the Kadian won't be quite as much on a milligram-for-milligram basis, but the exact ratio is impossible to predict with good accuracy. Methadone 20 mg is roughly equivalent to 10 parenteral morphine, but again there's lots of individual variation.

2007-08-17 12:53:03 · answer #1 · answered by Anonymous · 0 0

I even have been prescribed the two at one time or yet another. Percocet and lortab are the two soreness killers that do their job nicely. Percocet could make you dizzy and could probable provide you the experience of a rocking feeling. make certain you drink a lot of water with the two a form of because of fact they might reason constipation. do no longer take the two jointly because of fact there's a possiblity of combating your heart. keep away from using different drugs that make you sleepy (consisting of chilly drugs, soreness medicine, muscle relaxers, and medicines for seizures, melancholy or rigidity). indicators of an overdose might comprise severe drowsiness, muscle weak point, nausea, vomiting, sweating, confusion, chilly and clammy epidermis, shallow respiratory, sluggish heart fee, fainting, or coma. the two a form of will make you very sleepy. particular, they may well be relatively stable in case you have no tolerance to medicine, yet i does no longer difficulty too a lot approximately it. in basic terms save music of your indicators and drink a lot of fluids. no longer alcohol. in case you have anymore questions, be at liberty to touch me.

2016-10-02 13:20:12 · answer #2 · answered by ? 4 · 0 0

methadone....it killed anna nicole for christ sake as well as her son|!@

2007-08-17 12:39:04 · answer #3 · answered by mercedesofladies36 2 · 0 0

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