How is Wellbutrin different from SSRI's? What does it do if not adjust seratonin?

Answer 1

Check out this website. It gives way more information than you will ever needs about bupropion and its mode of action.
http://en.wikipedia.org/wiki/Wellbutrin#Mode_of_action

Answer 2

This Site Might Help You.

RE:
How is Wellbutrin different from SSRI's? What does it do if not adjust seratonin?

Answer 3

Bupropion Ssri

Answer 4

Wellbutrin is different because it isnt an SSRI it is an aminoketone. It is believed to balance the levels of dopamine and norepinephrine in the brain. It is frequently is prescribed to people with ADHD as well as depression. It has a stimulant effect so thats why it is also used to treat ADHD and why it is different from other SSRIs.

Answer 5

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Because there is no exclusively proven relationship between serotonin levels and depression. It is an old belief that is untrue according to many recent research studies. . SSRI's are thought by many to work as they can reduce anxiety (fear and negative thinking) in some people. Also brain neurotransmitters number about 200- serotonin is just one of them- and they would need to test all of them to get a true and accurate picture of what is going on in the brain. Many studies in neuroscience have not shown a co relation between neurotransmitter levels and reporting of depression. Many psychotropics are prescribed just in hopes that they will work for someone. Recent research has shown that many SSRI's are no more effective than placebos (sugar pills) in mild to moderate depressive patients. On many antidepressant package info you will find the statement that "the mechanism of action is unknown) meaning that it is not known entirely how or why they are effective in some people. Hope this info is helpful. Read neuroscience journals and goole "Antidepressants" for detailed info that tells you a great deal more about this matter.

Answer 6

Hi. Wellbutrin works mainly on the chemical dopamine while SSRI's work on mainly seratonin and norepinephrine. That's why some people who have not responded well to SSRI's sometimes respond very well to Wellbutrin, because it targets a different chemical.

Answer 7

I have been on several anti-depressants and Wellbutrin was the first one that worked for me. It did not drug me out. It made me feel like getting up and doing something other than just sitting and looking at the walls. I was so depressed I would just sit in my house for weeks, months and not even want to go anywhere. It has some side effects although. I can not stand to be around cigarette smoke. My daughter says I am mean and has since quit smoking.

Answer 8

Research suggests that depression may be caused by an imbalance of brain chemicals called neurotransmitters. Scientists believe that WELLBUTRIN XL helps balance the levels of two of these neurotransmitters called dopamine and norepinephrine.

When you have depression, nothing is more important than getting effective treatment. Clinical studies prove that WELLBUTRIN XL effectively treats depression so you can feel like yourself again. In addition, continued use (if recommended by your doctor) can lower your chances of becoming depressed in the future. Doctors have prescribed WELLBUTRIN XL to help millions of patients with depression. Although no single antidepressant works for everyone, the active ingredient in WELLBUTRIN XL (bupropion HCl) is prescribed more by psychiatrists than any other antidepressant. If you want effective treatment for depression, ask your doctor if WELLBUTRIN XL is right for you.


Definition of SSRI

SSRI: Abbreviation for selective serotonin reuptake inhibitors, commonly prescribed drugs for treating depression. SSRIs affect the chemicals that nerves in the brain use to send messages to one another. These chemical messengers, called neurotransmitters, are released by one nerve and taken up by other nerves. Neurotransmitters that are not taken up by other nerves are taken up by the same nerves that released them. This process is termed "reuptake." SSRIs work by inhibiting the reuptake of serotonin, an action which allows more serotonin to be available to be taken up by other nerves.

The most commonly prescribed SSRIs as of 1999 were paroxetine (brandname Paxil), fluoxetine (brandname Prozac) and sertraline (brandname Zoloft).

All three of these SSRIs appear equally efficacious, according to a 1999 study. The rate of patients switching from one class of drugs to another did not differ among the drug classes studied and there was no significant difference in the proportion of patients who switched from an SSRI to another SSRI (or another type of antidepressant), regardless of whether paroxetine (Paxil), fluoxetine (Prozac) or sertraline (Zoloft) was the initial therapy. These three SSRIs therefore are "equivalent in their effectiveness" but they "...are not interchangeable, because patients who discontinue one SSRI for lack of tolerability or response can generally be treated effectively with another." (Reference: J Clin Psychiatry 1999;60:574-579.)

Answer 9

Does Wellbutron cause weight gain