What are examples of drugs that affect the nervous synpase?

Answer 1

• Nicotine – This has an excitatory effect on postsynaptic cell. In large concentrations it can block synaptic transmission after initial stimulation.
• Caffeine – This inhibits action of an enzyme, phosphodiesterase, resulting in an increased intracellular concentration of cyclic AMP. Can results in the release of increased amounts of excitatory transmitter substances in the brain and had a mild stimulatory effect, increasing alertness.
• Opiates – This acts on the brain by binding to specific receptors, thus reducing the response to painful stimuli.

Answer 2

There are many drugs that act on the synapse.
Dopamine antagonists like haloperidol block dopaminergic neurotransmission and are used to treat schizophrenia. In contrast L-dopa a dopamine agonist is used to treat Parkinsons.
SSRI's don't directly effect the synapse, instead they block the uptake of the natural neurotransmitter serotonin thus prolonging its action. They are used for the treatment of depression.
A selective serotonin agonist is Sumatriptan this is used to treat migraine.
Benzodiazepines like valium act on the GABA receptor and are used to treat anxiety.

Answer 3

SSRI drugs.