what huntingtons disease?

Answer 1

Huntintingtons disease is an inherited genetic disease, where the brain is attacked. acoding to winpedicka
encyclopedia online, this is a short explanation for it:
Degeneration of neuronal cells, especially in the frontal lobes, the basal ganglia, and caudate nucleus (the striatum) occurs. There is also astrogliosis and loss of medium spiny neurons. This results in the selective degeneration of the indirect (inhibitory) pathway of the basal ganglia, via the lateral pallidum and the subthalamic nucleus coupled pacemaker system.

Phisical manifastations of it are called chorea, they inclued short jerky like movments, lack of coordination, exaggerated facial gestures, inability to swallow and sometimes chew. change in gait (how a peron walks.

Cognitive manifistaitions include the ability to talk properly, cognitive, critical, and abstract thinking. perceptual and spacial skills also falter, and strange mouth movments can occur.

Emotional manifestaions include anxiety, deppression, aggresive behaivor,and compulsivness.

Again from Wikipeda Encycopedia the genetic factor
Huntington's disease is autosomal dominant, needing only one affected allele from either parent to inherit the disease. Although this generally means there is a one in two chance of inheriting the disorder from an affected parent, the inheritance of HD and other trinucleotide repeat disorders is more complex.

When the gene has more than 36 copies of the repeated trinucleotide sequence, the DNA replication process becomes unstable and the number of repeats can change in successive generations. If the gene is inherited from the mother, the count is usually similar. Paternal inheritance tends to increase the number of repeats.[6] Because of the progressive increase in length of the repeats, the disease tends to increase in severity and have an earlier onset in successive generations. This is known as anticipation.

I hope this helps. I know that this disease is devistating, but I do belive they have genetic tests for it. The onset is usually well after 50. All my best
Chris

Answer 2

It is called Huntington's Chorea. Chorea is a condition characterized by involuntary, purposeless, rapid motions, as flexing & extending the fingers, raising & lowering the shoulders or facial grimacing. In some forms, the person is irritable, emotionally unstable, weak, restless,and, fretful. This is an autosomal ( any condition transmitted by an autosome, any chromosome ( DNA makeup) that is not a sex chromosome. Man has 22 pairs of autosomes, which are involved in transmitting all genetic traits and conditions). Huntington's Chorea thus is an autosomal hereditary, progressive degenerative disease, and is characterized by chorea and mental deterioration progressing to dementia( a progressive mental disorder characterized by chronic personality disintergration, confusion, disorientation, deterioration of intellectual capacity and function, and impairment of control of memory, judgment, and, impulses.) Symptoms usually appear between 30 and 40 years of age.Death can occur in about 15years. I hope that this information was helpful. Here are two websites:

en.wikipedia.org/wiki/Huntington's_ disease

www.mayoclinic.com/health/huntingtons_ disease/DS00401

Answer 3

Huntington's chorea is an inherited disease of the central nervous system, which has its onset between 30-50 years of age. The person suffers from progressive dementia with involountary movements of chorea. There is no cure, and it is terminal.

Answer 4

Huntington's Chorea is a degenerative nerve disease. Woody Guthrie died from it. It is fatal, but advancements are being made in the study of it, because we are living in the age of medical miracles, thankfully.

Answer 5

Often called Huntington's Syndrome. I knew someone with it vaguely, I guess it was something neurological. He was very small and had very limited uses of his hands, his hands were constantly half closed. He was also deaf. He died before he was 12, it was tragic, he was so lovely - I know everyone always says that about people who have passed, but he really was.

Answer 6

neurolgical disease.often run in the family ,usually manifest around 40 years with abnormal movement

Answer 7

I have a cousin with this illness. Here's a really good link to information.

Answer 8

My friends mother has it.
It can be passed down the family.
You cannot walk properly, and it effects your muscles, and your speech.
I think it varies though.

Answer 9

What is google?