What is the R variable in the molecular formula of the Penicillin nucleus...R-C9 H11 N2 O4 S ?
2007-07-16 19:07:22 · 4 answers · asked by CHAZ 2 in Science & Mathematics ➔ Medicine
Example of its variable would be the substituents (R) on the aromatic rings of oxacillin, cloxacillin, and
flucloxacillin which do not participate significantly in the electron withdrawing properties of the heterocycle but rather influence drug absorption and plasma protein binding.
That would make:
Oxacillin: R = R' =H
Cloxacillin: R= Cl,R' = H
Flucloxacillin: R = Cl,R' = F
For more variables check out this link and look under the penicillin:
http://userwww.sfsu.edu/~cberkman/640_notes_3.2_antibact.pdf
2007-07-20 04:25:35 · answer #1 · answered by ♥ lani s 7 · 0⤊ 0⤋
different radicals, some proprietary, trhat can be stuck on to the nucleus to change absorption and liver metabolism and half life.
2007-07-23 01:07:32 · answer #2 · answered by Anonymous · 0⤊ 0⤋
r is the alphabetical mention in the chemical name
2007-07-23 14:22:18 · answer #3 · answered by mbck_786 1 · 0⤊ 0⤋
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2007-07-21 21:55:52 · answer #4 · answered by eddie9551 5 · 0⤊ 0⤋