Wat antigen-antibody reaction endpoint results when complement is activated? Why is that important?

Answer 1

The end point would be attacking or destruction of the invader.The complement system consists of a number of small proteins found in the blood, which work together to kill target cells by disrupting the target cell's plasma membrane. In immune system it is important to protect from invading organisms by helping to clear pathogens from an organism.

Answer 2

Complement binds to the antigen-antibody complex to enhance phagocytosis. Therefore, complement helps the antigen be attacked faster. Why is that important? Do I really have to answer that part? That seems fairly obvious why it's important to destroy the antigen as fast as possible.

Answer 3

Complement helps eliminate pathogens from the body in 3 ways. 1) Activation of complement on the pathogen itself can lead to formation of the membrane attack complex (MAC), which forms a pore in the pathogen's plasma membrane--this causes death of the pathogen. 2) Complement can "opsonize" a pathogen--makes the pathogen easier to be phagocytosed (and destroyed) by macrophages. 3) Small complement fragments (C3a, C4a, C5a) generated during the complement activation cascade are chemoattractants--they attract other white blood cells to the site of infection (and the more white blood cells you have at the infection site, the quicker and more efficiently you can destroy all of the pathogens.)