Can Prednisone jack up a full blood count test. Namely my platelet count & that test included thyroid funct.?

Question

I have 2 herniated disc & take Prednisone & get cortisone shots in my spine These medications are not long term & cycle as needed because of the sides. Some of my test came back real elevated. I had a platelet count of 700+. I guess I had a over active thyroid because it was like .03 or something like that. All I know is that it's over active. Can someone explain please…

I'm sorry I think that would be 700K

Answer 1

The normal platelet count is 150,000. The platelets are needed for coagulation to prevent bleeding. It mediates in clot or fibrin formation. So with platelet count so low; bleeding time is prolonged. Corticosteroids such as Prednisone ( it's converted to prednisolone ny the liver) and cortisone are used to suppress the immune system and inflammation. such as in bursitis. It is also used in treatment of thrombocytopenia by raising the platelet count. Your platelet count of 700,000 is unusually high. Another minor side effects is overactivity as it overactivates your thyroid.


Prednisone and prednisolone are members of the glucocorticoid class of hormones. This means they are steroids but, unlike the anabolic steroids that we hear about regarding sports medicine, these are "catabolic" steroids. Instead of building the body up, they are designed to break down stored resources (fats, sugars and proteins) so that they may be used as fuels in times of stress. Cortisone would be an example of a related hormone with which most people are familiar. Glucocorticoids hormones are produced naturally by the adrenal glands.

We do not use the glucocorticoids for their influences on glucose and protein metabolism; we use them because they are also the most broadly anti-inflammatory medications that we have. Their uses fit into several groups:

Anti-inflammatory (especially for joint pain and itchy skin)

Immune-suppression (treatment of conditions where the immune system is destructively hyperactive. Higher doses are required to actually suppress the immune system)

Cancer Chemotherapy (especially in the treatment of lymphoma)

Central Nervous System Disorders (usually after trauma or after a disc episode to relieve swelling in the brain or spinal cord ) as in your case.

Shock (steroids seem to help improve circulation)

Blood Calcium Reduction (in medical conditions where blood calcium is dangerously high treatment is needed to reduce levels to normal)
Prednisone is activated by the patient's liver into Prednisolone.

Prednisolone may be administered in tablet form or produced by the body from prednisone. These medications are considered to be interchangeable.

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Glucocorticoid hormone use can be irritating to the stomach at higher doses.

INTERACTIONS WITH OTHER DRUGS

Glucocorticoid hormones should not be used in combination with medications of the NSAID class (ie aspirin, Rimadyl, phenylbutazone etc.) as the combination of these medications could lead to bleeding in the stomach or intestine. Ulceration could occur.

CONCERNS AND CAUTIONS

Prednisone and prednisolone are considered to be intermediate acting steroids, meaning that a dose lasts about a day or a day and a half. After two weeks or more of use, it is important to taper the dose to an every other day schedule so as to keep the body's own cortisone sources ( body's own adrenal glands) able and healthy.


Prednisone/Prednisolone use is likely to change liver enzyme blood testing and interfere with testing for thyroid diseases.

When prednisone/prednisolone is used routinely, serious side effects would not be expected. When doses become immune-suppressive (higher doses) or use becomes "chronic" (longer than 4 months at an every other day schedule), the side effects and concerns associated become different. In these cases, monitoring tests may be recommended or, if possible, another therapy may be selected.

Answer 2

Important information

Prednisone treats many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.
You should not take prednisone if you have a fungal infection anywhere in your body.
Steroid medication can weaken your immune system, making it easier for you to get an infection. Avoid being near people who are sick or have infections. Do not receive a "live" vaccine while using prednisone.
Call your doctor at once if you have shortness of breath, severe pain in your upper stomach, bloody or tarry stools, severe depression, changes in personality or behavior, vision problems, or eye pain.
You should not stop using prednisone suddenly. Follow your doctor's instructions about tapering your dose.


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